Ernährung & Medizin 2021; 36(01): 39-42
DOI: 10.1055/a-1253-6071
Praxis

Enzymsubstitution bei onkologischen Patienten mit exokriner Pankreasinsuffizienz

Nicole Pedros Frank
,
Barbara Scheerer
,
Nicole Erickson

Zusammenfassung

Vorgestellt wird der Fall einer 57-jährigen Frau mit einem Adenokarzinom des Pankreaskorpus. Dies erforderte eine operative Entfernung des Pankreas und in der Folge eine Substitution der Pankreasenzyme und des Insulins. Trotz guter Insulineinstellung und Compliance bei der Einnahme der verordneten Pankreasenzyme nahm die Patientin kontinuierlich ab. Wie kann hier eine Ernährungsberatung aussehen?



Publication History

Article published online:
17 March 2021

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  • Literatur

  • 1 Arends J, Bachmann P, Baracos V. et al. ESPEN guidelines on nutrition in cancer patients. Clinical Nutrition 2017; 36: 11-48
  • 2 Vujasinovic M, Valente R, Del Chiaro M. et al. Pancreatic exocrine insufficiency in pancreatic cancer. Nutrients 2017; 9: 183
  • 3 Lindkvist B. Diagnosis and treatment of pancreatic exocrine insufficiency. World J Gastroenterol 2013; 19: 7258-7266
  • 4 Ferrone M, Raimondo M, Scolapio JS. Pancreatic enzyme pharmacotherapy. Pharmacotherapy 2007; 27: 910-920
  • 5 Sabater L, Ausania F, Bakker OJ. et al. Evidence-based guidelines for the management of exocrine pancreatic insufficiency after pancreatic surgery. Ann Surg 2016; 264: 949-958
  • 6 Mössner J, Keim V. Pancreatic enzyme therapy. Dtsch Arztebl Int 2010; 108: 578-582
  • 7 Halloran CM, Cox TF, Chauhan S. et al. Partial pancreatic resection for pancreatic malignancy is associated with sustained pancreatic exocrine failure and reduced quality of life: a prospective study. Pancreatology 2011; 11: 535-545
  • 8 Sikkens ECM, Cahen DL, van Eijck C. et al. The daily practice of pancreatic enzyme replacement therapy after pancreatic surgery: a northern European survey: enzyme replacement after surgery. J Gastrointest Surg 2012; 16: 1487-1492
  • 9 Berry AJ. Pancreatic enzyme replacement therapy during pancreatic insufficiency. Nutr Clin Pract 2014; 29: 312-321
  • 10 Layer P, Keller J, Lankisch PG. Pancreatic enzyme replacement therapy. Curr Gastroenterol Rep 2001; 3: 101-108
  • 11 Kuhn R J, Gelrud A, Munck A. et al. CREON (Pancrelipase Delayed-Release Capsules) for the treatment of exocrine pancreatic insufficiency. Adv Ther 2010; 27: 895-916
  • 12 FDA; U. S. Food and Drug Administration. Highlights of prescribing information (CREON). Im Internet: https://www.accessdata.fda.gov/drugsatfda_docs/label/2009/020725s000lbl.pdf