Intensivmedizin up2date, Table of Contents Intensivmedizin up2date 2021; 17(02): 131-136DOI: 10.1055/a-1335-1071 SOP / Arbeitsablauf SOP ICU-acquired Weakness (Critical-Illness-Polyneuropathie/Critical-Illness-Myopathie) Authors Hubertus Axer Albrecht Günther Recommend Article Abstract Buy Article(opens in new window) All articles of this category(opens in new window) In dieser Rubrik stellen wir Standard Operating Procedures (SOPs) für häufige, intensivmedizinisch relevante Prozesse vor. Die Form ist eher im Sinne einer Schablone zu verstehen als – durchaus subjektiv gefärbte – Anregung, eigene, auf lokale Gegebenheiten adaptierte stationsinterne SOPs zu entwerfen und zu implementieren. Full Text References Literatur 1 Kress JP, Hall JB. ICU-Acquired Weakness and Recovery from Critical Illness. N Engl J Med 2014; 370: 1626-1635 2 Brunkhorst F, Axer H. What are the Causes of and how do I treat critical Illness Neuropathy/Myopathy?. In: Deutschman CS, Neligan PJ. eds. Evidence-Based Practice of critical Care. 3rd ed.. Amsterdam: Elsevier; 2020: 208-214.e1 3 Hermans G, Van den Berghe G. Clinical review: intensive care unit acquired weakness. Crit Care 2015; 19: 274 4 Stevens RD, Dowdy DW, Michaels RK. et al. Neuromuscular dysfunction acquired in critical illness: a systematic review. Intensive Care Med 2007; 33: 1876-1891 5 Latronico N, Fenzi F, Recupero D. et al. Critical illness myopathy and neuropathy. Lancet 1996; 347: 1579-1582 6 De Jonghe B, Sharshar T, Lefaucheur J-P. et al. Paresis acquired in the intensive care unit: a prospective multicenter study. JAMA 2002; 288: 2859-2867 7 Latronico N, Bolton CF. Critical illness polyneuropathy and myopathy: a major cause of muscle weakness and paralysis. Lancet Neurol 2011; 10: 931-941 8 Fan E, Cheek F, Chlan L. et al. An official American Thoracic Society Clinical Practice guideline: the diagnosis of intensive care unit-acquired weakness in adults. Am J Respir Crit Care Med 2014; 190: 1437-1446 9 Hermans G, Clerckx B, Vanhullebusch T. et al. Interobserver agreement of Medical Research Council sum-score and handgrip strength in the intensive care unit. Muscle Nerve 2012; 45: 18-25 10 Grimm A, Günther A, Witte OW. et al. Critical-Illness-Polyneuropathie und Critical-Illness-Myopathie. Med Klin Intensivmed Notfmed 2012; 107: 649-660 11 Lacomis D. Electrophysiology of neuromuscular disorders in critical illness. Muscle Nerve 2013; 47: 452-463 12 Lefaucheur J-P, Nordine T, Rodriguez P. et al. Origin of ICU acquired paresis determined by direct muscle stimulation. J Neurol Neurosurg Psychiatr 2006; 77: 500-506 13 Weber-Carstens S, Koch S, Spuler S. et al. Nonexcitable muscle membrane predicts intensive care unit-acquired paresis in mechanically ventilated, sedated patients. Crit Care Med 2009; 37: 2632-2637 14 Bierbrauer J, Koch S, Olbricht C. et al. Early type II fiber atrophy in intensive care unit patients with nonexcitable muscle membrane. Crit Care Med 2012; 40: 647-650 15 Grimm A, Teschner U, Porzelius C. et al. Muscle ultrasound for early assessment of critical illness neuromyopathy in severe sepsis. Crit Care 2013; 17: R227 16 Khan J, Harrison TB, Rich MM. et al. Early development of critical illness myopathy and neuropathy in patients with severe sepsis. Neurology 2006; 67: 1421-1425 17 Moss M, Yang M, Macht M. et al. Screening for critical illness polyneuromyopathy with single nerve conduction studies. Intensive Care Med 2014; 40: 683-690 18 Hermans G, De Jonghe B, Bruyninckx F. et al. Interventions for preventing critical illness polyneuropathy and critical illness myopathy. Cochrane Database Syst Rev 2014; (01) CD006832 19 Brunkhorst FM, Engel C, Bloos F. et al. Intensive insulin therapy and pentastarch resuscitation in severe sepsis. N Engl J Med 2008; 358: 125-139 20 Brunner R, Rinner W, Haberler C. et al. Early treatment with IgM-enriched intravenous immunoglobulin does not mitigate critical illness polyneuropathy and/or myopathy in patients with multiple organ failure and SIRS/sepsis: a prospective, randomized, placebo-controlled, double-blinded trial. Crit Care 2013; 17: R213