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Ernährung & Medizin 2021; 36(02): 68-76
DOI: 10.1055/a-1483-2924
DOI: 10.1055/a-1483-2924
Wissen
Vitamin-D-Versorgung und die Gesundheit von schwangeren Frauen und Kindern bis zum Schulalter
Zusammenfassung
Die derzeitige Studienlage weist Unklarheiten in Bezug auf Folgen einer Vitamin-D-Unterversorgung für Mutter und Kind sowie Plasma-Referenzwerte für Vitamin D und Aufnahmeempfehlungen auf. Die vorliegende Studie untersucht auf Basis einer systematischen Suche und Metaanalyse die Evidenzlage zum Zusammenhang von mütterlichem und kindlichem Vitamin D mit bestimmten gesundheitlichen Endpunkten.
Publication History
Article published online:
08 June 2021
© 2021. Thieme. All rights reserved.
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Literatur
- 1 Dietary reference values for vitamin D. EFSA Journal 2016; 14: e04547 DOI: 10.2903/j.efsa.2016.4547.
- 2 Principi N, Bianchini S, Baggi E. et al. Implications of maternal vitamin D deficiency for the fetus, the neonate and the young infant. Eur J Nutr 2013; 52: 859-867 DOI: 10.1007/s00394-012-0476-4.
- 3 Deutsche Gesellschaft für Ernährung. Ausgewählte Fragen und Antworten zu Vitamin D. Im Internet: https://www.dge.de/wissenschaft/weitere-publikationen/faqs/vitamin-d/?L=0 (Stand: 22.10.2012)
- 4 Holick MF. Vitamin D deficiency. N Engl J Med 2007; 357: 266-281 DOI: 10.1056/NEJMra070553.
- 5 Vitamin D Referenzwerte D-A-CH. Im Internet: https://www.dge.de/wissenschaft/referenzwerte/vitamin-d/?L=0 (Stand: 13.03.2021)
- 6 Liu NQ, Hewison M. Vitamin D, the placenta and pregnancy. Arch Biochem Biophys 2012; 523: 37-47 DOI: 10.1016/j.abb.2011.11.018.
- 7 Hollis BW, Johnson D, Hulsey TC. et al. Vitamin D supplementation during pregnancy: double-blind, randomized clinical trial of safety and effectiveness. J Bone Miner Res 2011; 26: 2341-2357 DOI: 10.1002/jbmr.463.
- 8 Akbari S, Khodadadi B, Ahmadi SAY. et al. Association of vitamin D level and vitamin D deficiency with risk of preeclampsia: A systematic review and updated meta-analysis. Taiwanese J Obstet Gynecol 2018; 57: 241-247 DOI: 10.1016/j.tjog.2018.02.013.
- 9 Palacios C, Kostiuk LK, Peña-Rosas JP. Vitamin D supplementation for women during pregnancy. Cochrane Database Syst Rev. 2019 DOI: 10.1002/14651858.CD008873.pub4
- 10 Hu Z, Tang L, Xu H-L. Maternal vitamin D deficiency and the risk of small for gestational age: A Meta-analysis. Iran J Public Health 2018; 47: 11
- 11 Bi WG, Nuyt AM, Weiler H. et al. Association between vitamin D supplementation during pregnancy and offspring growth, morbidity, and mortality: A systematic review and meta-analysis. JAMA Pediatrics 2018; 172: 635 DOI: 10.1001/jamapediatrics.2018.0302.
- 12 Tous M, Villalobos M, Iglesias L. et al. Vitamin D status during pregnancy and offspring outcomes: a systematic review and meta-analysis of observational studies. Eur J Clin Nutr 2019; 74: 36-53 DOI: 10.1038/s41430-018-0373-x.
- 13 Maugeri A, Barchitta M, Blanco I. et al. Effects of vitamin D supplementation during pregnancy on birth size: A systematic review and meta-analysis of randomized controlled trials. Nutrients 2019; 11: 442 DOI: 10.3390/nu11020442.
- 14 Wei Z, Zhang J, Yu X. Maternal vitamin D status and childhood asthma, wheeze, and eczema: A systematic review and meta-analysis. Pediatr Allergy Immunol 2016; 27: 612-619 DOI: 10.1111/pai.12593.
- 15 Pacheco-González RM, García-Marcos L, Morales E. Prenatal vitamin D status and respiratory and allergic outcomes in childhood: A meta-analysis of observational studies. Pediatr Allergy Immunol 2018; 29: 243-253 DOI: 10.1111/pai.12876.
- 16 Amraei M, Mohamadpour S, Sayehmiri K. et al. Effects of vitamin D deficiency on incidence risk of gestational diabetes mellitus: A systematic review and meta-analysis. Front Endocrinol 2018; 9: 7 DOI: 10.3389/fendo.2018.00007.
- 17 Pérez-López FR, Pasupuleti V, Mezones-Holguin E. et al. Effect of vitamin D supplementation during pregnancy on maternal and neonatal outcomes: a systematic review and meta-analysis of randomized controlled trials. Fertil Steril 2015; 103: 1278-1288.e4 DOI: 10.1016/j.fertnstert.2015.02.019.
- 18 Wang J, Liu N, Sun W. et al. Association between vitamin D deficiency and antepartum and postpartum depression: a systematic review and meta-analysis of longitudinal studies. Arch Gynecol Obstet 2018; 298: 1045-1059 DOI: 10.1007/s00404-018-4902-6.
- 19 Shi D, Wang D, Meng Y. et al. Maternal vitamin D intake during pregnancy and risk of asthma and wheeze in children: a systematic review and meta-analysis of observational studies. J Maternal-Fetal Neonat Med 2019; 34: 653-659 DOI: 10.1080/14767058.2019.1611771.
- 20 Aghajafari F, Nagulesapillai T, Ronksley PE. et al. Association between maternal serum 25-hydroxyvitamin D level and pregnancy and neonatal outcomes: systematic review and meta-analysis of observational studies. BMJ 2013; 346: f1169 DOI: 10.1136/bmj.f1169.
- 21 Hu L, Zhang Y, Wang X. et al. Maternal vitamin D status and risk of gestational diabetes: a meta-analysis. Cell Physiol Biochem 2018; 45: 291-300 DOI: 10.1159/000486810.
- 22 Lu M, Xu Y, Lv L. et al. Association between vitamin D status and the risk of gestational diabetes mellitus: a meta-analysis. Arch Gynecol Obstet 2016; 293: 959-966 DOI: 10.1007/s00404-016-4010-4.
- 23 Zhang M-X, Pan G-T, Guo J-F. et al. Vitamin D deficiency increases the risk of gestational diabetes mellitus: A meta-analysis of observational studies. Nutrients 2015; 7: 8366-8375 DOI: 10.3390/nu7105398.
- 24 Poel YHM, Hummel P, Lips P. et al. Vitamin D and gestational diabetes: A systematic review and meta-analysis. Eur J Intern Med 2012; 23: 465-469 DOI: 10.1016/j.ejim.2012.01.007.
- 25 Ojo O, Weldon SM, Thompson T. et al. The effect of vitamin D supplementation on glycaemic control in women with gestational diabetes mellitus: A systematic review and meta-analysis of randomised controlled trials. IJERPH 2019; 16: 1716 DOI: 10.3390/ijerph16101716.
- 26 Jahanjoo F, Farshbaf-Khalili A, Shakouri SK. et al. Maternal and neonatal metabolic outcomes of vitamin D supplementation in gestational diabetes mellitus: A systematic review and meta-analysis. Ann Nutr Metab 2018; 73: 145-159 DOI: 10.1159/000491643.
- 27 Rodrigues MRK, Molina Lima SA, Ferreira da Silvia Mazeto GM. et al. Efficacy of vitamin D supplementation in gestational diabetes mellitus: Systematic review and meta-analysis of randomized trials. PLoS One 2019; 14: e0213006 DOI: 10.1371/journal.pone.0213006.
- 28 Shen S-Y, Xiao W-Q, Lu J-H. et al. Early life vitamin D status and asthma and wheeze: a systematic review and meta-analysis. BMC Pulm Med 2018; 18: 120 DOI: 10.1186/s12890-018-0679-4.
- 29 Bi WG, Nuyt AM, Weiler H. et al. Association between vitamin D supplementation during pregnancy and offspring growth, morbidity, and mortality: A systematic review and meta-analysis. JAMA Pediatr 2018; 172: 635 DOI: 10.1001/jamapediatrics.2018.0302.
- 30 Haussler MR, Whitfield GK, Kaneko I. et al. Molecular mechanisms of vitamin D action. Calcif Tissue Int 2013; 92: 77-98 DOI: 10.1007/s00223-012-9619-0.
- 31 Berridge MJ. Vitamin D and depression: Cellular and regulatory mechanisms. Pharmacol Rev 2017; 69: 80-92 DOI: 10.1124/pr.116.013227.
- 32 Dusso AS, Brown AJ, Slatopolsky E. Vitamin D. Am J Physiol Renal Physiol 2005; 289: F8-F28 DOI: 10.1152/ajprenal.00336.2004.
- 33 Schedel M, Jia Y, Michel S. et al. 1,25D3 prevents CD8 + Tc2 skewing and asthma development through VDR binding changes to the Cyp11a1 promoter. Nat Commun 2016; 7: 10213 DOI: 10.1038/ncomms10213.
Weitere Literatur zu den im systematischen Review bzw. in den Metaanalysen eingeschlossenen Studien bei den Verfasserinnen.