Akutes Leberversagen bei einem Hund nach Aufnahme eines Pilzes, vermutlich der Gattung Amanita

Zusammenfassung

Ein 4 Jahre alter, männlich-kastrierter, 29,4 kg schwerer Husky-Mischling, der am Tag zuvor einen Pilz, wahrscheinlich der Gattung Amanita. gefressen hatte, wurde mit Diarrhö, Vomitus, Inappetenz und zunehmender Apathie vorgestellt. Labordiagnostisch ließen sich Hypoglykämie, Hyperbilirubinämie, erhöhte Leberenzymaktivitäten sowie verminderte Gerinnungsfaktoraktivitäten (veränderte Prothrombinzeit und aktivierte partielle Thromboplastinzeit) feststellen. Trotz stationärer symptomatischer Therapie über 3 Tage verschlechterte sich das Allgemeinbefinden des Hundes und er wurde euthanasiert. Die pathomorphologischen Befunde waren durch Blutungen in mehreren Organen, blutige Ingesta, Ikterus und hochgradige Leberzellnekrosen gekennzeichnet.

Abstract

A 4-year-old, neutered male Husky-mix dog weighing 29.4 kg that reportedly ingested a mushroom most likely of the genus Amanita one day prior to presentation exhibited signs of diarrhea, vomitus, inappetence and progressively worsening lethargy. Clinical chemistry revealed hypoglycemia, hyperbilirubinemia, decreased prothrombin and thromboplastin time, as well as increased liver enzyme activities. Despite hospitalization and supportive therapy over a period of 3 days the dog’s general condition worsened leading to euthanasia. The pathomorphological findings were characterized by hemorrhage in several organs, hemorrhagic ingesta, icterus, and marked hepatic cellular necrosis.

Schlüsselwörter

Intoxikation - Amatoxin - Pilzvergiftung - Leberzellnekrose

Key words

Intoxication - amatoxin - mushroom poisoning - liver cell necrosis

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