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Kinder- und Jugendmedizin 2022; 22(05): 324-332
DOI: 10.1055/a-1908-5561
DOI: 10.1055/a-1908-5561
Schwerpunkt
Neue Aspekte zur Therapie des Dravet-Syndroms
New aspects for the therapy of Dravet syndrome
ZUSAMMENFASSUNG
Das Dravet-Syndrom ist gekennzeichnet durch eine schwer behandelbare Epilepsie und assoziierte Komorbiditäten. Nun stehen neben Stiripentol mit Cannabidiol und Fenfluramin zwei neue und spezifische Therapieoptionen zur Verfügung. In diesem Beitrag erfolgt ein Überblick über die gebräuchlichsten und neuen Antikonvulsiva, deren Wirkung, Sicherheitsprofil sowie die potenziellen Interaktionen.
ABSTRACT
Dravet syndrome is characterized by drug resistant epilepsy and associated comorbidities. In addition to stiripentol, cannabidiol and fenfluramine are now available as new and specific therapeutic options. In this review, we provide an overview of the most common and new anticonvulsants, and their efficacy, safety profile, and potential interactions.
Publication History
Article published online:
08 November 2022
© 2022. Thieme. All rights reserved.
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