Keywords
algorithm - female - vulva - cosmetic surgery - review
Introduction
Despite the reservations harbored by various physicians and behavioral therapists
regarding female genital aesthetic surgery,[1]
[2]
[3] labia minora reduction has become a mainstream treatment in economically flourishing
societies.[3] The number of registered labiaplasties in the United States, for example, has increased
sevenfold over the last decade, from 2142 in 2011 to 14,386 in 2020.[4] Parallel to the increase, a variety of labiaplasty techniques have been developed,
presented, and reflected on. Because all have their advantages and limitations, no
single one technique will offer the optimal solution for every patient.[5]
[6]
[7]
[8]
[9]
[10] Rather, the technique should be chosen in accordance with the expectations and anatomical
features of each individual patient.[5]
[10]
[11]
[12]
[13]
[14]
To date, some classifications have been presented to guide this choice, most of them
based on labia minora width measurement,[15] labial configuration,[10]
[13]
[16] or a combination of both.[8]
[17] Only very few authors actually paired the various classes with various labiaplasty
techniques, thereby offering a true algorithm.[6]
[10]
[18] None of these algorithms incorporated patients' preferences regarded maintenance
of the labial free rim, maintenance of labial sensitivity, and prevention of iatrogenic
thickening of the labium. Still, any one of these considerations may be of particular
interest to the patient.
The purpose of this study was to elucidate these considerations and establish an algorithm
for choice of labia minora reduction technique based on them. To do so, we found we
had to (re-)define some of the terms used regarding labiaplasty. The terms width and length,[10]
[14]
[19]
[20]
[21] for instance, are used inconsistently for what would in French medical literature
and stereometrically be referred to as “height.”[22]
[23]
[24] Furthermore, we (re-)assessed the considerations relevant to the choice of labiaplasty
technique.
Definitions
Anteriorly, each labium minus divides into a lateral and a medial skin fold. The bilateral
medial folds unite at the clitoral glans to form the clitoral frenulum, whereas both
lateral folds unite over the clitoris to form the clitoral hood, or prepuce. Likewise,
both minor labia are often connected with each other posteriorly, rounding the vaginal
introitus as the labial frenulum, or fourchette. In a strict sense, the length of
a labium minus should thus be measured from the median at the clitoral hood anteriorly,
to the median at the fourchette posteriorly.[24] Still, for this work we defined the length relevant for labiaplasty as the measurement
along the free rim of the labium minus from the point of transition of frenulum to
labium anteriorly to the point where the fourchette leaves the medial aspect of the
labium majus posteriorly ([Fig. 1]).[25]
[26]
Fig. 1 The clinically relevant length for labiaplasty was defined as the measurement along
the free rim of the minor labium from the frenulum division anteriorly (green arrows)
to the point where the fourchette leaves the medial aspect of the major labium posteriorly
(red arrows).
The width of the labium minus was defined as the distance from its lateral base where
the labium minus borders the labium majus in the interlabial sulcus, to the outer
most part of its free rim when not stretched. The measure of protrusion of the labium
minus past the labium majus, however, is clinically more relevant for labiaplasty.
The thickness of the labium minus was defined as the mediolateral distance between
the medial and lateral skin surface of the labium.
In cases where skin folds extend anteriorly from the labium minus proper to longitudinally
run lateral and parallel to the clitoral hood, these folds were regarded as the paralabial
folds (plis paranymphéaux) recorded by Jayle, in 1918.[22] These seem to correspond with the “secondary labia,”[27] “accessory labia,”[19] “redundant lateral labium,”[28] or “lateral hood folds.”[29] These are not to be confused with a relative surplus of prepuce
[13]
[18]
[28] that may occur in combination with, or apart from paralabial folds ([Fig. 2]). Finally, longitudinal skin folds extending posteriorly past the point where the
fourchette leaves the labium majus are referred to as commissural folds (plis commissureaux).[22] For reasons of comprehensibility, our algorithm is restricted to the choice of technique
of labia minora reduction. Thus, possible correction of the clitoral hood, posterior
fourchette, paralabial folds, or commissural folds are to be considered separately
when applicable.
Fig. 2 A relative surplus of preputium (red arrow) is not to be confused with paralabial
folds (both green arrows).
Patient's Considerations
Patients and physicians may consciously or subconsciously differ in opinion as to
the aesthetics of labia minora.[5]
[10]
[14]
[20]
[28]
[30]
[31] Like holds true for all aesthetic considerations, cultural influences (e.g., peers,
media, art) largely define accepted standards of normality.[13]
[20]
[26]
[32] Most women in Western culture perceive a symmetrical vulva with minor labia and
a clitoral hood tucked inside the major labia as normal.[10]
[32] Still, the surgeon needs to assess whether the patient wants her minor labia to
sit flush with, or entirely hidden by the major labia.[33] Yurteri-Kaplan et al,[32] furthermore, suggested an age-related difference in patients' expectations. They
found younger women to perceive the nongaping introitus featured by popular media
as normal, whereas older women may desire restoration of prior individual appearance
and anatomy. Moreover, some women prefer to have a darker pigmented free edge removed
because they associate it with an aged appearance,[30] whereas others prefer to keep this natural aesthetic.[7] Significant pigmentation variation from the labia free rim inward, furthermore,
may warrant edge preservation particularly in women of color.[29] Because of the wide spectrum of patient considerations and expectations, every patient's
aesthetic or functional goals ought to be identified before a surgical technique can
be decided on.[7]
[10]
[16]
[21]
[29]
[34]
[38]
Configurational Considerations
Configurational Considerations
Even though the request to rid the patient from any protrusion of the labium minus
past the major labium may appear simple, the surgeon also has to consider the variation
in labium minus configuration.[8]
[14]
[16]
[35] This configuration may be classified according to the location of the protrusion
or relative surplus of tissue.[6]
[8]
[9]
[18]
[35]
[36] As such, we differentiate between predominately anterior protrusion,[8]
[10]
[14]
[18]
[30]
[35] predominately middle protrusion,[10]
[30]
[35] predominately posterior protrusion,[10]
[35] and anteroposteriorly generalized protrusion.[8]
[18]
[30]
Anatomical Considerations
Anatomical Considerations
Accurate understanding of the labial neurovascular system may improve the surgical
approach and outcome of labium reduction.[24]
[37]
[38] Salmon has been the first to record the labial vascular system by his meticulous
and systematic radiographic studies of the integumental vascularization, in 1936.[39] He found the anterior one-third of the labia minora to be perfused by a branch deriving
from the external pudendal artery and the posterior two-thirds by small internal pudendal
branches that run perpendicular to the labial long axis ([Fig. 3]). He recorded the two systems to anastomose and form an arcade along the labial
free rim.[39]
Fig. 3 In 1936, Michel Salmon recorded the anterior one-third of the minor labia to be perfused
by a branch deriving from the external pudendal artery and the posterior two-thirds
by small internal pudendal branches that run perpendicular to the labial long axis.
The two systems anastomose to form an arcade along the labial free rim. Note that
central arteries may bilaterally be observed running to the most protruding part of
the labial free rim. (Reproduced by kind permission from G.I. Taylor and M.N. Tempest,
editors. Michel Salmon's Arteries of the Skin. London, UK: Churchill Livingstone;
1988).
In accordance with Salmon's radiographic study, Georgiou et al[36] more recently identified one dominant central, and three lesser arteries to originate from the internal pudendal system in 9 specimens.
This central artery ran up to the labial free rim to continue along it in anterior direction and
anastomose with external pudendal branches. These findings, in turn, were generally
supported by a translabial illumination study by Kaya et al.[9] These authors, however, stressed that the position of the central artery predominately depends on the localization of maximum labial protrusion, rather
than it being centrally located in all cases.[9] Hence, their observations appear to oppose Alter's stressing the importance of excising
the most enlarged part of the labium minus,[40] as this will significantly reduce the remaining labial vascularization.
Georgiou et al,[36] furthermore, observed that the labial arteries run superficially under the skin,
thus refuting the central core vascularization of the labium minus conceptualized
by Heusse et al[23] and supported by the observations by Ginger et al.[37] Consequently, they warned that central de-epithelialization techniques present some
risk of labial ischemia as the vessels may be injured.[36]
Still, Ginger et al[37] concluded that the number of vascular structures in the minor labia is much more
than what would be expected to maintain baseline vascular sufficiency for such small
skin folds. This is supported by the lack of ischemia after splitting of the inner
and outer aspect of the labium to allow opposite transplantation of each, in 70 metaidoioplasties.[41] In other words, labial vascularization is rich and its local interruption will seldom
result in ischemia in women without potential circulatory risk factors such as tobacco
abuse, diabetes mellitus, or other vascular disorders.[6]
[28]
[42]
[43] In heavy smokers and other women at risk, preoperative cold light assisted labial
transillumination may be helpful to assess and map the labial vascular supply.[9]
The sensory innervation of the labium minus may be a point of more concern. Internal
and external pudendal nerve branches innervating the labium minus accompany the vascular
ramifications and tend to course most readily along the free rim of the labium.[37]
[44] Labial innervation is unidirectional and its transection may result in loss of sensibility
in part of the labium possibly affecting sexual function or,[10]
[28] worse, in neuroma formation along the suture line.[25] Because both the pudendal labial innervation and the dorsal clitoral innervation
seem to convers to the clitoral frenulum, surgeon and patient alike ought to accept
this frenulum to be a surgical no go area. It is our experience, in women as in men, that incising the frenulum easily results
in neuroma formation with symptoms that are near impossible to treat.
Technical Considerations
Edge resection, wedge excision, and central de-epithelialization have been recognized,
modified, and combined over the last four decennia as the three principal techniques
for labial reduction ([Fig. 4]). It is generally agreed that no reduction technique should decrease the remaining
labial width to less than 1 cm measured from the interlabial sulcus.[10]
[11]
[20]
[29]
[31]
[45]
[46] Suspension of the lateral most tip of the minor labium may help plan and execute
the reduction.[21]
[31]
[38]
Fig. 4 Edge resection, wedge excision, and central de-epithelialization are the three principal
techniques for minor labial reduction. (A) Edge resection or trimming involves the straightforward amputation of protuberant tissues. Note that it additionally
reduces the labial free rim length. (B) Straight amputation has been modified to a running W-resection to ensure a more robust
and natural appearing rim after reduction. (C) Wedge excision involves the resection of a triangular part of skin at both the lateral
and medial aspect of the labium minus. Note that it may correct a surplus of labial
free rim length but only partly corrects labial width. (D) The initially central wedge excision has been modified to the dorsal wedge excision
and anterior flap technique. Note that this modification also lowers the labial width
and that the resulting scar runs less conspicuously along the base of the labium minus.
(E) Central de-epithelialization involves the partial skinning of the medial and lateral
aspects of the labium from its introital base, respectively, the interlabial sulcus
outward. It may also be executed as a full-thickness resection or fenestration. Note that this will not reduce the labium free rim length.
Edge resection or trimming involves the straightforward amputation of protuberant tissues. It additionally reduces
the labial free rim length ([Fig. 4A]) and is adaptable to virtually any labial size or shape.[29] It removes the possibly pigmented or corrugated free edge of the labium. Of the
three principal techniques, trimming features the smallest risk of dehiscence. It
potentially increases the risk of tenderness during sexual intercourse and scar contracture,[6] but such sequences have never been validated.[29]
[46] Straight amputation has been modified to a running W-resection to ensure a more
robust and natural appearing rim postoperatively ([Fig. 4B]).[31]
[45]
Wedge excision basically involves the resection of a triangular part of skin at both
the lateral and medial aspect of the labium. The base of the triangle is located along
the rim of the most protruding part of the labium.[12]
[30] The top of the triangle to be excised is pointing toward the interlabial sulcus
on the lateral aspect and toward Hart's line on the medial aspect. Wedge resection
may correct a surplus of labial length but only partly corrects labial width ([Fig. 4C]).[11] It saves the appearance of the remaining parts of the free labial edge. This may
result in an abrupt transition of a more bulky, pigmented, or corrugated anterior
edge to a finer and less pigmented posterior edge.[28] Likewise, an abrupt change of pigmentation may occur along the perpendicular scar,
particularly on the medial aspect of the labium minus.[12]
[28] Alter's central wedge excision technique has been modified to the dorsal wedge excision
and anterior flap technique by Rouzier et al.[47] The resulting scar then runs posterior and less conspicuous along the base of the
labium minus. Munhoz et al,[5] Smarrito,[18] and Yang and Hengshu[10] further modified the anterior flap design to additionally reduce labial width ([Fig. 4D]). Of the three principal techniques, full-thickness wedge excision features the
greatest wound dehiscence risk with reported prevalences of 7 to 14%.[5]
[47] Consequently, Alter more recently advocated restricting the technique to wedge de-epithelialization
rather than full-thickness resection.[28]
Central de-epithelialization involves the partial skinning of the medial and lateral
aspects of the labium from its introital base, respectively, the interlabial sulcus
outward ([Fig. 4E]).[11] This will decrease labial width but not the length of its free rim, which potentially
results in festooning of the rim.[12]
[28] Central de-epithelialization may result in a longitudinal line of abrupt change
of coloration where the epithelium is reapproximated and some authors have argued
that the longitudinal scar created by this technique may distort the labia.[12]
[31] Again, the latter sequence has not been validated to date.[46] De-epithelialization techniques, in general, are applied to save the neurovascular
supply. They also save all, or part, of the subcutaneous bulk and likely result in
telescoping
[48] of the remaining labial tissues and increased thickness of all but the least protruding
minor labia.[6]
[12]
[28]
[29]
[46]
[48] Additionally, such telescoping may increase the risk of wound dehiscence. When done
as a full-thickness resection rather than a de-epithelialization,[13]
[42] however, wound dehiscence will even result in fenestration.[42] Furthermore, the risk of loss of neurovascular supply to the free rim then lurks.[12]
Combined wedge excision and central de-epithelialization was suggested as a bidimensional technique[48] and as custom flask labiaplasty.[35] Comparable addition of medial anterior and posterior triangular wedges to be excised
perpendicular to the principal wedge had already been suggested by Alter, as early
as 1998,[30] and this may be considered the full-thickness equivalent of the custom flask labiaplasty.
Smarrito[18] and Yang and Hengshu[10] introduced three further modifications of the wedge excision design, whereas Jiang
et al[34] reported combining a medial wedge excision with a partial edge resection. With these
combined techniques, the authors tried to prevent remaining labial protrusion,[10]
[18]
[30]
[34]
[35]
[48] festooning of remaining labial rim length,[10]
[18]
[34]
[35]
[48] free rim alteration,[10]
[18]
[48] loss of neurovascular supply,[34]
[35] and wound dehiscence.[34]
Algorithmic Decisional Steps
Algorithmic Decisional Steps
We propose to start the choice of labiaplasty technique by establishing whether or
not the free rim of the labium is to be resected partially, entirely, or not at all
([Fig. 5]). This may be of particular interest in women who present with labial asymmetry.
In these, it has to be decided whether to reduce only the wider labium and preserve
the entire rim to optimally match the contralateral one, or perform an asymmetrical
bilateral reduction that may include bilateral (partial) rim resection. Reasons for
entire resection include unwanted pigmentation and a corrugated appearance of the
rim. Preservation of the entire rim is preferred to prevent a scar crossing the rim
or a sudden change of pigmentation between its anterior and posterior parts. Partial
rim resection may be indicated in cases where unwanted corrugation, pigmentation,
or protrusion is restricted to part of the rim.
Fig. 5 Flowchart of the proposed algorithm for the choice of reduction labiaplasty technique.
Second, the width to be resected needs be considered in candidates for (partial) rim
preservation. Obviously, this width to be resected equals the labial width with which
the woman presents, minus the width that is preferred by her. In cases where this
width of resection is limited to 1 cm, the reduction may be done by de-epithelialization
without the risk of conspicuous thickening of the labium. More extended reductions
de-epithelialization tends to result in such thickening.
Next, circulatory risk factors are to be assessed and weighed. To reduce postoperative
ischemic complications such as wound dehiscence and partial necrosis, de-epithelialization
techniques are to be preferred over excision in heavy smokers and otherwise vascular
compromised women. This implies that vascular compromised women in whom the intended
width reduction is more than 1 cm are to accept iatrogenic thickening of their labium.
Furthermore, possible festooning of the rim is to be accepted in such women in whom
the entire rim is preserved. In cases where this is not accepted, preoperative labial
transillumination may help design a safer resection.[9]
In non-vascular compromised women in whom the intended width reduction is more than
1 cm, on the other hand, the risk of loss of labial sensitivity associated with central
excisional techniques has to be weighed against the risk of labial thickening associated
with de-epithelialization techniques.
Last, the technique for labiaplasty is paired to the location of the corrugation,
pigmentation, or protrusion to be resected in candidates for partial rim resection.
Algorithmic Choice of Labiaplasty Technique
Algorithmic Choice of Labiaplasty Technique
The outcome of the decisional steps of our algorithm includes edge resection according
to Maas and Hage and Solanki et al[31]
[45] ([Fig. 6A]), central de-epithelialization or fenestration ([Fig. 6B]), according to Choi and Kim,[11] da Cunha et al,[13] and Laub,[42] and one out of three modifications of wedge resection or de-epithelialization. These
modifications are:
-
- Modified anterior wedge resection combined with posterior flap transposition according
to Yang and Hengshu's method A,[10] and its de-epithelialization execution according to Alter[28] ([Fig. 6C]);
-
- Posterior wedge resection combined with anterior flap transposition according to
Munhoz et al,[5] Smarrito's Lambda technique,[18] and Yang and Hengshu's method C,[10] and its de-epithelialization modification according to Tremp et al[38] ([Fig. 6D]);
-
- Custom flask de-epithelialization according to Gonzalez et al[35] and its full-thickness resection modification as proposed by Alter,[30] in cases of predominately middle disfigurement or protrusion ([Fig. 6E]).
Fig. 6 Artist impression of preoperative markings (left) and postoperative outcome (right)
of each of the techniques included in the algorithm. The shaded area on the left side
represents the part of the labia to be de-epithelialized or resected prior to: (A) Running W-resection of the labial rim; (B) Central de-epithelialization or fenestration. Note that this will not reduce the
labium free rim length; (C) Modified anterior wedge de-epithelialization or resection combined with posterior
flap transposition; (D) Posterior wedge de-epithelialization or resection combined with anterior flap transposition;
(E) Custom flask de-epithelialization or full-thickness resection.
Preoperative and postoperative clinical examples of each of these techniques have
amply been illustrated in the original publications by the various authors.[5]
[11]
[18]
[28]
[31]
[35]
[38]
[45]
The Algorithm in Historical Perspective
The Algorithm in Historical Perspective
To date, only three groups of authors offered a true algorithm for choice of labiaplasty
technique by pairing various classes of labial features with various reduction techniques.[6]
[10]
[18] As such, Ellsworth et al[6] adopted the classification based on absolute labial width as proposed by Franco
and Franco[15] for their choice of technique. They applied the central de-epithelialization technique
according to Choi and Kim[11] to reduce labia presenting with up to 4 cm (Franco Classes 1 and 2) and the inferior
wedge technique according to Munhoz et al[5] in labia over 6 cm wide (Franco Class 4). Franco Class 3 labia (of 4–6 cm width)
was preferably treated by lazy-S edge trimming according to Felicio,[49] but the inferior wedge technique was applied in those women who preferred to retain
the natural labial edge.[6] Hence, their algorithm was based exclusively on absolute labial measurements, disregarding
configurational variations and remaining protrusion associated with wedge resection.
Smarrito[18] used a classification based on the location of the relative surplus of tissue as
applied previously by Gonzalez et al[35] and González,[8] and subsequently by Kaya et al[9] and Hamori and Stuzin.[16] He distinguished type I with anterior third redundancy; type II with middle third
redundancy; and type III with posterior third redundancy. An anterior redundancy was
treated by an incision along the posterior half of the labial rim, after which the
protruding anterior part was folded dorsally to be sutured to the incised edge of
the lower, most posterior part of the labium. Middle third redundancies were treated
with a slightly modified posterior wedge technique,[47] whereas Smarrito combined his Lambda posterior resection and anterior flap technique for a posterior redundancy.[18] Thus, the anterior half of the labial rim was used to replace the resected posterior
rim in all patients, regardless of its appearance or patients' preferences.
Yang and Hengshu[10] introduced a more extensive classification system according to the location of labial
redundancy. They distinguished six configurational types: 1—anterior protrusion; 2—central
protrusion; 3—posterior protrusion; 4—redundant anterior–posterior labial length;
5—generalized width and length redundancy; and 6—labial protrusion combined with preputial
redundancy. To treat types 1 to 5, the authors suggested three different techniques
of reduction: A—full labial resection except for a posteriorly based, rectangular
edge flap that was used to replace all of the excised tissue for types 1 and 5 redundancies;
B—full labial resection except for both an anterior and a posteriorly based rectangular
edge flap that were used to replace all of the excised tissue for a type 2 redundancy;
C—full labial resection except for an anteriorly based, triangular edge flap that
was used to replace all of the excised tissue for types 3, 4, and 5 redundancies.
For type 6 combined labial and preputial redundancy, the authors suggested two additional
techniques.[10] Hence, their algorithm was based solely on the presenting labial configuration without
consideration of labial color and texture,[21]
[46] or postoperative rim appearance, labial sensitivity, and pigmentation changes.
The algorithm we propose is based on individualized anatomical, configurational, and
personal considerations, which can be applied unilaterally or bilaterally. In this
algorithm, normative classifications of labial width are ignored. From the available
normative datasets on labia minora width measurements[19]
[27]
[33] may be concluded that normal labial width varies enormously. Kreklau et al,[50] furthermore, observed a negative correlation between body mass index and labia minora
width and Gress[24] stressed how the level of the interlabial sulcus can vary in relation to the vestibulum.
Therefore, absolute width measurement cannot be used as a possible base for surgical
decisions.[18] Rather, the request often concerns any measure of protrusion of the labia minora
beyond the labia majora.[8]
[20]
[46] In the vast majority of women, this request is aesthetically driven.[29]
[30]
[47] Some of these women may be reassured by explaining that their labial features are
within a normal range and loose interest in labiaplasty (the so-called desisters), but an increasing number of them will persist in their wish for labiaplasty despite
such explanation (the persisters).[33] Like rhinoplasty, mammaplasty, and lipofilling that all usually adjust features
that are within a normal range, reduction labiaplasty has become one possibility in
an ever increasing array of aesthetic operations.
Given this, it is our task to improve and extend our techniques and assure that each
individual patient obtains an optimal result.[10]
[29] The labiaplasty surgeon can no longer hide behind the adage to use the one technique you are most confident with because of the various, possibly conflicting, considerations present in each patient.[10] Consequently, the surgeon working with our proposed algorithm is required to master
modifications of all three conventional reduction techniques, each to be executed
either by excision or by de-epithelialization.
Potential Pitfalls of Reduction Labiaplasty
Potential Pitfalls of Reduction Labiaplasty
Although the minor labia are usually the focus of patients' concerns, achieving a
desirable cosmetic outcome may require additional external genital alterations. When
not discussed, failure to concurrently address an explicit clitoral hood may result
in the patient complaining of a masculine, penile appearance.[29]
[40] On the other hand, unsolicited concurrent reduction in the clitoral hood or posterior
fourchette may result in aesthetic disappointment or, worse, in complaints or disorders
of sexual function. Hence, it is wise to evaluate the entire anatomic region—minor
labia, major labia, clitoral hood, perineum, and mons pubis—during the consultation
of women seeking labiaplasties.[24]
[29] Any involvement of the clitoral prepuce and posterior fourchette, in particular,
needs to be considered preoperatively. Reduction in the prepuce may be achieved by
separate longitudinal,[17] transverse,[29] or combined longitudinal and transverse resections,[42] or by extension of the design of reduction of the lateral labial aspect toward the
prepuce.[13]
[28]
[29] Even though some authors record that reduction in the fourchette can be performed
equally simple by direct resection,[10]
[17]
[18] others regard the fourchette a surgical no go area.[11]
[20]
[30]
[46] We consider fourchette trimming to feature the risk of contracture of a scar that
crosses transversely over the posterior introitus which, in turn, may obliterate the
introitus. Therefore, we advocate including multiple Z-plasties when preforming posterior
fourchette trimming.
Future Perspectives and Conclusion
Future Perspectives and Conclusion
Future algorithms may be additionally proposed for the assessment and treatment of
the other female genital structures. Still, the decision on technique for the reduction
in the labium proper can best be reached separately from considerations regarding
the other aspects of female genital aesthetic surgery. We feel that the five steps
to be considered and the inclusion of modifications of all three conventional reduction
techniques in the algorithm offer an improvement over previously presented algorithms.
