Ultrasound Elastography for Characterization of Focal Liver Lesions

Yi Dong; Jonas Koch; Amjad Alhyari; Ehsan Safai Zadeh; Christian Görg; Wen-Ping Wang; Annalisa Berzigotti; Christoph F. Dietrich

doi:10.1055/a-1957-7370

Zeitschrift für Gastroenterologie, Table of Contents

Z Gastroenterol 2023; 61(04): 399-410
DOI: 10.1055/a-1957-7370

Übersicht

Ultrasound Elastography for Characterization of Focal Liver Lesions

Elastografie zur Charakterisierung von Lebertumoren

Yi Dong

¹Department of Ultrasound, Zhongshan Hospital Fudan University, Shanghai, China (Ringgold ID: RIN92323)

²Department of Ultrasound, Xinhua Hospital Affiliated to Shanghai Jiaotong University School of Medicine, Shanghai, China

,

Jonas Koch

³Department Allgemeine Innere Medizin, Kliniken (DAIM) Hirslanden Beau Site, Salem und Permanence, Bern, Switzerland

,

Amjad Alhyari

⁴Interdisciplinary Center of Ultrasound Diagnostics, University Hospital Giessen and Marburg, Gastroenterology, Endocrinology, Metabolism and Clinical Infectiology, Philipps University Marburg, Marburg, Germany (Ringgold ID: RIN61061)

,

Ehsan Safai Zadeh

⁴Interdisciplinary Center of Ultrasound Diagnostics, University Hospital Giessen and Marburg, Gastroenterology, Endocrinology, Metabolism and Clinical Infectiology, Philipps University Marburg, Marburg, Germany (Ringgold ID: RIN61061)

,

Christian Görg

⁴Interdisciplinary Center of Ultrasound Diagnostics, University Hospital Giessen and Marburg, Gastroenterology, Endocrinology, Metabolism and Clinical Infectiology, Philipps University Marburg, Marburg, Germany (Ringgold ID: RIN61061)

,

Wen-Ping Wang

¹Department of Ultrasound, Zhongshan Hospital Fudan University, Shanghai, China (Ringgold ID: RIN92323)

,

Annalisa Berzigotti

⁵Department of Visceral Surgery and Medicine, Bern University Hospital, University of Bern, Berne, Switzerland

,

Christoph F. Dietrich

³Department Allgemeine Innere Medizin, Kliniken (DAIM) Hirslanden Beau Site, Salem und Permanence, Bern, Switzerland

› Author Affiliations

Abstract

Focal liver lesions (FLL) are typically detected by conventional ultrasound or other imaging modalities. After the detection of FLL, further characterization is essential, and this can be done by contrast-enhanced imaging techniques, e.g., contrast-enhanced ultrasound (CEUS) and magnetic resonance imaging (MRI) or by means of biopsy with histological evaluation. Elastographic techniques are nowadays integrated into high-end ultrasound systems and their value for the detection of severe liver fibrosis and cirrhosis has been shown in studies and meta-analyses. The use of an ultrasound elastographic technique for the differentiation of malignant and benign liver tumors is less well-established. This review summarizes the current data on utility and performance of ultrasound elastography for the characterization of FLL.

Zusammenfassung

Fokale Leberläsionen (FLL) werden typischerweise durch konventionellen Ultraschall oder andere bildgebende Verfahren detektiert. Eine weitere Charakterisierung erfolgt durch kontrastverstärkte bildgebende Verfahren, z. B. kontrastverstärkter Ultraschall (CEUS) und Magnetresonanztomografie (MRT), oder durch Biopsie mit histologischer Untersuchung. Elastografische Techniken werden heute routinemäßig in Ultraschallsysteme integriert und ihr Wert für die Erkennung der fortgeschrittenen Leberfibrose und -zirrhose wurde in Studien, Metaanalysen und Leitlinien belegt. Weniger etabliert ist der Einsatz elastografischer Techniken zur Differenzierung bösartiger und gutartiger Lebertumoren. Dieser Review fasst die aktuellen Daten zur Bedeutung der Ultraschall-Elastografie zur Charakterisierung von FLL zusammen.

Schlüsselwörter

Elastografie - fokale Leberläsionen - Lebertumoren - Steifheit - Ultraschall

Keywords

Elastography - focal liver lesions - liver tumors - stiffness - Ultrasound

Full Text

References

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