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Ultraschall Med 2023; 44(06): 650-651
DOI: 10.1055/a-1978-5690
Letter to the Editor

Letter to the Editor Regarding the Article “Contrast-Enhanced Ultrasound Liver Imaging Reporting and Data System in Diagnosing Hepatocellular Carcinoma: Diagnostic Performance and Interobserver Agreement” by Zhou and Collaborators

The low diagnostic prediction capacity of CEUS LR-M class for a specific tumor is not a problem but rather perhaps an advantage
Bernardo Stefanini 
1   Department of Medical and Surgical Sciences, University of Bologna, Italy
,
Eleonora Terzi
2   Division of Internal Medicine, Hepatobiliary and Immunoallergic Disease, IRCCS Azienda Ospedaliero-Universitaria di Bologna Policlinico S Orsola, Bologna, Italy
,
Alice Giamperoli
1   Department of Medical and Surgical Sciences, University of Bologna, Italy
,
Federico Ravaioli
1   Department of Medical and Surgical Sciences, University of Bologna, Italy
,
Fabio Piscaglia 
1   Department of Medical and Surgical Sciences, University of Bologna, Italy
2   Division of Internal Medicine, Hepatobiliary and Immunoallergic Disease, IRCCS Azienda Ospedaliero-Universitaria di Bologna Policlinico S Orsola, Bologna, Italy
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Letter to:

Response to Letter to the Editor Regarding the Article “Contrast-Enhanced Ultrasound Liver Imaging Reporting and Data System in Diagnosing Hepatocellular Carcinoma: Diagnostic Performance and Interobserver Agreement” by Zhou and CollaboratorsUltraschall Med 2023; 44(06): 652-653
DOI: 10.1055/a-1979-0808

We read with great interest the article by Zhou and collaborators about the interobserver agreement in CEUS LI-RADS classification published this year in Ultraschall in der Medizin (Zhou H. et al. Ultraschall in Med 2022 Feb; 43: 64–71). The study is well designed and well conducted, and the authors are to be commended for their valuable efforts. The results are relevant and in line with previous studies (Terzi E. et al. J Hepatol. 2018; 68: 485–492) (Schellhaas B. et al. Eur Radiol 2018; 28: 4252–4264) and show moderate to limited reproducibility in the assignment of CEUS LI-RADS classes, mainly due to differences in the determination of the timing and degree of washout and to a lesser extent also in the presence and patterns of arterial phase hyperenhancement.



Publication History

Accepted Manuscript online:
14 November 2022

Article published online:
19 April 2023

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