Molekulare Biomarker bei neuroinflammatorischen Erkrankungen

Biomarker gelten als Schlüsselelement für die Umsetzung von Präzisionsmedizin. Technische Fortschritte in der Quantifizierbarkeit von ZNS-Molekülen im peripheren Blut und im Design von klinischen Studien zur Identifizierung und Validierung von Biomarkern haben in den letzten Jahren zu einer starken Dynamik in der Biomarkerentwicklung sowohl bei entzündlichen als auch bei degenerativen Erkrankungen des Nervensystems geführt. Die vorliegende Übersicht fasst den aktuellen Stand und Entwicklungslinien zu molekularen Biomarkern bei entzündlichen neurologischen Erkrankungen zusammen.

Schlüsselwörter

Diagnostik - Multiple Sklerose - Neuromyelitis optica (NMOSD) - Myelin-Oligodendrozyten-Glykoprotein-Antikörper-Krankheit (MOGAD - Autoimmunenzephalitis - Myasthenia gravis

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