Diagnostik des Guillain-Barré-Syndroms – Schritt für Schritt

Das akute Guillain-Barré-Syndrom ist ein heterogenes Syndrom mit unterschiedlichen klinischen Bildern und unterschiedlicher Pathophysiologie. Der Beitrag zeigt die diagnostischen Schritte bei der Untersuchung des häufigsten Subtyps der akuten inflammatorischen demyelinisierenden Polyneuropathie.

Schlüsselwörter

GBS - Guillain-Barré-Syndrom - Nervenleitgeschwindigkeit - Muskelaktionspotenziale

Publication History

Article published online:
06 March 2025

• Literatur

• 1 Leonhard SE, Mandarakas MR, Gondim FAA. et al. Diagnosis and management of Guillain–Barré syndrome in ten steps. Nat Rev Neurol 2019; 15: 671-683
• 2 Uncini A, Ippoliti L, Shahrizaila N. et al. Optimizing the electrodiagnostic accuracy in Guillain-Barré syndrome subtypes: criteria sets and sparse linear discriminant analysis. Clin Neurophysiol 2017; 128: 1176-1183
• 3 Weber F. The diagnostic sensitivity of different F wave parameters. J Neurol Neurosurg Psychiatry 1998; 65: 535-540
• 4 Preston DC, Shapiro BE. Electromyography and neuromuscular disorders: clinical-electrophysiologic correlations. 3. edn. London: Elsevier; 2013
• 5 Uncini A, Kuwabara S. The electrodiagnosis of Guillain-Barré syndrome subtypes: where do we stand?. Clin Neurophysiol 2018; 129: 2586-2593
• 6 Nandedkar SD, Sanders DB, Hobson-Webb LD. et al. The extrapolated reference values procedure: theory, algorithm, and results in patients and control subjects. Muscle Nerve 2017; 57: 90-95
• 7 Nandedkar SD, Mansukhani K, More N. et al. Revising nerve conduction reference limits. Muscle Nerve 2021; 64: 99-103
• 8 Rajabally YA, Hiew FL. Optimizing electrodiagnosis for Guillain-Barré syndrome: clues from clinical practice. Muscle Nerve 2017; 55: 748-751