Abstract
Background With the introduction of optical coherence tomography (OCT) in glaucoma imaging,
the neuroretinal tissue of the retina and optic nerve head can be measured and quantified
at different measuring points, much more accurately than with previous imaging techniques.
In addition to macular parameters such as the macular and peripapillary thickness
of the retinal nerve fibre thickness and the macular ganglion cell layer thickness,
parameters close to the papillary were also defined, as based on the Bruchʼs membrane
opening (BMO), and examined with regard to their suitability for glaucoma diagnostics.
This overview presents the advantages and disadvantages of these parameters in glaucoma
diagnostics.
Materials and Methods Review of current literature in PubMed as well as synopsis of relevant guidelines.
Results and Conclusion The minimum marginal width of the Bruchʼs membrane opening (BMO-MRW) is the most
frequently used OCT parameter for measuring the neuroretinal marginal width of the
optic nerve head. There are also area parameters. Compared to peripapillary RNFL thickness
and macular parameters, BMO-MRW has equivalent to superior sensitivity in glaucoma
detection. In the longitudinal view, effects such as changes in the eye pressure level
lead to fluctuations in BMO-MRW, which limits the usefulness of this parameter with
regard to morphometric progression analysis. Numerous studies have shown that peripapillary
nerve fibre layer thickness (pRNFL) is better suited for progression analysis. Checking
the automatic segmentation of OCT images is relevant for all OCT parameters in glaucoma
diagnostics.
Keywords
OCT - Glaucoma - glaucoma imaging - Bruchʼs membrane opening
