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Int J Angiol 2025; 34(03): 201-210
DOI: 10.1055/a-2572-1026
Original Article

Outcome of Redo Endovascular Interventions in Cases of Infra-inguinal Arterial Occlusive Disease

Authors

  • Khaled Mohamed Fekry

    1   Department of Vascular Surgery, Faculty of Medicine, Cairo University, Cairo, Egypt

  • Sherif Balbaa

    1   Department of Vascular Surgery, Faculty of Medicine, Cairo University, Cairo, Egypt

  • Ahmed Saeed

    1   Department of Vascular Surgery, Faculty of Medicine, Cairo University, Cairo, Egypt

  • Ahmed Alaa Shaker

    1   Department of Vascular Surgery, Faculty of Medicine, Cairo University, Cairo, Egypt
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Abstract

The aim was to assess the outcomes of different redo endovascular interventions in terms of wound healing and limb salvage within 6 months. From April 2024 to October 2024, a prospective clinical study was carried out on 56 patients who presented with chronic limb-threatening ischemia (CLTI) after previous peripheral endovascular intervention 6 months to 1 year earlier. Regarding technical success, restored linear blood flow from common femoral artery (CFA) to foot was higher in stenting and drug-coated balloon (DCB) than plain old balloon angioplasty (POBA) (p value = 0.032 and 0.033 respectively). Restoration of pedal pulse was statistically higher in DCB than in stenting (p value = 0.006) and higher in stenting than POBA (p value = 0.003). Wound healing at time frame of 3 months after the operation was statistically higher in DCB than POBA and stenting (p value = 0.002 and 0.007 respectively) and higher in stenting than POPA (p value = 0.033). Regarding amputation-free survival, above ankle amputation within 6 months of follow-up was lower in stenting and DCB than POBA (p value = 0.016 and 0.018 respectively) and there was no statistical difference between stenting and DCB (p value = 0.166). Stenting and DCBs have demonstrated a superior ability than POBA to restore linear blood flow from the CFA to the foot, leading to better amputation-free survival rates, including a decreased likelihood of above ankle amputation within the first 6 months of follow-up. When it comes to wound healing and sustaining limb-based patency, DCB angioplasty has shown better performance compared with stenting and POBA.

Keywords

redo - endovascular - angioplasty - infra-inguinal - CLTI - DCB - POPA

Authors' Contributions

A.S. was involved in writing, data collection, and revision of the manuscript. A.S. and K.M.F. contributed to the revision and writing, while S.B. also participated in the revision and writing process. All authors read and approved the final version of the manuscript.


Ethical Approval

The study was approved by the ethics committee of Faculty of Medicine, Cairo University, Egypt.


Patients' Consent

An informed consent was obtained from each patient. There are adequate provisions to maintain privacy of the participants and confidentiality of the data. The patients were given the option of not participating in the study if they did not want to. All the data of the patients were kept confidential with secret codes and private file for each patient; all given data were used for current medical research only. Any unexpected risks that appeared during the research were cleared to the participants and the ethics committee on time.




Publication History

Article published online:
07 May 2025

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