Die feline Hepatolipidose

Die Hepatolipidose ist die häufigste Erkrankung der Leber bei der Katze. Mögliche Ursachen, Pathogenese und klinisches Bild sowie diagnostische und therapeutische Optionen werden im folgenden Beitrag ausführlich beschrieben.

Publikationsverlauf

Artikel online veröffentlicht:
26. August 2025

• Literatur

• 1 Watson PJ. Hepatobiliäre Erkrankungen der Katze. In: Nelson RW, Couto CG, Steffen T. Hrsg. Innere Medizin der Kleintiere. 6. Aufl.. München: Urban & Fischer/Elsevier; 2022: 548-553
• 2 Lam R, Niessen SJ, Lamb CR. X-ray attenuation of the liver and kidney in cats considered at varying risk of hepatic lipidosis. Vet Radiol Ultrasound 2014; 55: 141-146
• 3 Valtolina C, Robben JH, van Wolferen ME. et al. Gene expressions of de novo hepatic lipogenesis in feline hepatic lipidosis. J Feline Med Surg 2020; 22: 500-505
• 4 Minamoto T, Walzem RL, Hamilton AJ. et al. Altered lipoprotein profiles in cats with hepatic lipidosis. J Feline Med Surg 2019; 21: 363-372
• 5 Smith K. A nutritional approach to feline hepatic lipidosis (17.04.2018). https://www.veterinary-practice.com/article/a-nutritional-approach-to-feline-hepatic-lipidosis Stand: 01.06.2025
• 6 Kuzi S, Segev G, Kedar S. et al. Prognostic markers in feline hepatic lipidosis: a retrospective study of 71 cats. Vet Rec 2017; 181: 512
• 7 Wallace OP, Jablonski SA, Thomas JS. et al. Association of time to start of enteral nutrition and outcome in cats with hepatic lipidosis. J Vet Intern Med 2024; 38: 3144-3152
• 8 Valtolina C, Favier RP. Feline Hepatic Lipidosis. Vet Clin North Am Small Anim Pract 2017; 47: 683-702
• 9 Rutgers C, Biourge V. Die Ernährung von Katzen mit Erkrankungen der Leber und des exokrinen Pankreas. In: Pilot P, Biourge V, Elliot D. Enzyklopädie der klinischen Diätetik der Katze. Hannover: Schlütersche; 2009: 146-147 176–177
• 10 Verbrugghe A, Bakovic M. Peculiarities of one-carbon metabolism in the strict carnivorous cat and the role in feline hepatic lipidosis. Nutrients 2013; 5: 2811-2835
• 11 Center SA. Feline hepatic lipidosis. Vet Clin North Am Small Anim Pract 2005; 35: 225-269
• 12 Armstrong PJ, Blanchard G. Hepatic lipidosis in cats. Vet Clin North Am Small Anim Pract 2009; 39: 599-616
• 13 Blanchard G, Paragon BM, Milliat F. et al. Dietary L-carnitine supplementation in obese cats alters carnitine metabolism and decreases ketosis during fasting and induced hepatic lipidosis. J Nutr 2002; 132: 204-210
• 14 Center SA, Harte J, Watrous D. et al. The clinical and metabolic effects of rapid weight loss in obese pet cats and the influence of supplemental oral L-carnitine. J Vet Intern Med 2000; 14: 598-608
• 15 Webb CB. Hepatic lipidosis: Clinical review drawn from collective effort. J Feline Med Surg 2018; 20: 217-227
• 16 Center SA, Crawford MA, Guida L. et al. A retrospective study of 77 cats with severe hepatic lipidosis: 1975–1990. J Vet Intern Med 1993; 7: 349-359
• 17 Brown B, Mauldin GE, Armstrong J. et al. Metabolic and hormonal alterations in cats with hepatic lipidosis. J Vet Intern Med 2000; 14: 20-26
• 18 Dimski DS, Taboada J. Feline idiopathic hepatic lipidosis. Vet Clin North Am Small Anim Pract 1995; 25: 357-373
• 19 Center SA. Nutritional support for dogs and cats with hepatobiliary disease. J Nutr 1998; 128: 2733S-2746S
• 20 Wang KY, Panciera DL, Al-Rukibat RK. et al. Accuracy of ultrasound-guided fine needle aspiration of the liver and cytologic findings in dogs and cats: 97 cases (1990–2000). J Am Vet Med Assoc 2004; 224: 75-78
• 21 Griffin S. Feline abdominal ultrasonography: whatʼs normal? Whatʼs abnormal? The liver. J Feline Med Surg 2019; 21: 12-24
• 22 Willard MD, Weeks BR, Johnson M. Fine-needle aspirate cytology suggesting hepatic lipidosis in four cats with infiltrative hepatic disease. J Feline Med Surg 1999; 1: 215-220
• 23 Berent AC, Weisse C. Hepatic Vascular Anomalies. In: Ettinger SJ, Feldman EC. Textbook of Veterinary Internal Medicine. 7. Aufl.. Philadelphia (PA): Saunders Company; 2010: 1651-1654 1659–1661, 1681–1684
• 24 Lhotta K. Störungen des Phosphathaushaltes. Austrian J Clin Endocrinol Metab 2011; 4: 20-23
• 25 Wallace OP, Jablonski SA, Thomas JS. et al. Association of time to start of enteral nutrition and outcome in cats with hepatic lipidosis. J Vet Intern Med 2024; 38: 3144-3152
• 26 Brenner K, KuKanich KS, Smee NM. Refeeding syndrome in a cat with hepatic lipidosis. J Feline Med Surg 2011; 13: 614-617
• 27 Trepanier L. Acute vomiting in cats: rational treatment selection. J Feline Med Surg 2010; 12: 225-230
• 28 Bauer JE, Schenck PA. Nutritional management of hepatic disease. Vet Clin North Am Small Anim Pract 1989; 19: 513-526