Antibakterielle und antimykotische Wirkung einer pflanzlichen Hautschutzsalbe in vitro

Zusammenfassung

Einleitung

Scheuerstellen, Blasen oder eine Dermatitis entstehen, wenn die Haut mechanisch gereizt und beansprucht wird. Im schlimmsten Fall bilden sich Wunden, die sich infizieren können; daher ist es wichtig, die Hautbarriere zu schützen. Diese In-vitro-Studie wurde durchgeführt, um die antibakterielle und antimykotische Wirkung einer im Handel erhältlichen Hautschutzsalbe mit pflanzlichen Inhaltsstoffen (ilon Protect Salbe) zu untersuchen. Die Hauptinhaltsstoffe dieser Salbe sind Olivenöl, Lärchenterpentin, Eukalyptusöl und Thymianöl, die Salbenbasis besteht aus Vaseline und weißem Bienenwachs.

Methoden

Die antimikrobielle Wirkung des Produkts wurde bei 2,5- und 5%iger Konzentration der Salbe im Müller-Hinton-Medium mittels Tropfenverdünnungstest an den grampositiven Bakterien Staphylococcus aureus, einem Methicillin-resistenten S. aureus (MRSA), S. epidermidis, S. haemolyticus, Streptococcus pyogenes, dem gramnegativen Pseudomonas aeruginosa und den Hefen Candida albicans und C. tropicalis getestet.

Ergebnisse

Die 2,5%ige und die 5%ige Salbe zeigten beide eine Wirkung sowohl auf die humanpathogenen Candida albicans und C. tropicalis als auch auf Str. pyogenes und P. aeruginosa, aber nur mit der 5%igen Konzentration wurde eine Hemmung von MRSA und S. haemolyticus erreicht. Das Wachstum von S. aureus und S. epidermidis hingegen wurde nicht gehemmt.

Schlussfolgerungen

Die Hautpflegesalbe weist eine antimykotische und selektive antibakterielle Wirkung auf.

Abstract

Purpose

Chafing, blisters, or dermatitis occur when the skin is mechanically irritated and stressed. In the worst case, wounds can result and become infected. This in vitro study was conducted to investigate the antibacterial and antifungal effects of a commercially available skin protection ointment (ilon Protect Ointment) containing herbal ingredients. The main ingredients are olive oil, larch turpentine, eucalyptus oil, and thyme oil; the ointment base consists of petroleum jelly and white beeswax.

Methods

The antimicrobial effect of the product at 2.5% and 5% concentrations was tested in Müller-Hinton Agar using a drop dilution test on the Gram-positive bacteria Staphylococcus aureus, a methicillin-resistant S. aureus (MRSA), S. epidermidis, S. haemolyticus, Streptococcus pyogenes, the Gram-negative Pseudomonas aeruginosa, and the yeasts Candida albicans and C. tropicalis.

Results

Both 2.5% and 5% ointments were effective against the human pathogens Candida albicans and C. tropicalis as well as Str. pyogenes and P. aeruginosa, but only the 5% concentration inhibited MRSA and S. haemolyticus. S. aureus and S. epidermidis, on the other hand, grew in the presence of both concentrations.

Conclusions

The skin care ointment has an antifungal and selective antibacterial effect.

Schlüsselwörter

antibakterielle Wirkung - Hautirritationen - ätherische Öle - Dekubitus - Hautschutz

Keywords

antibacterial effect - skin irritations - essential oils - pressure ulcers - skin protection

Publication History

Received: 30 September 2025

Accepted after revision: 07 January 2026

Article published online:
19 February 2026

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