Zusammenfassung
Erkrankungen des Lymphsystems werden häufig durch klinische Untersuchungen diagnostiziert.
Bildgebende Verfahren erlauben darüber hinaus eine Objektivierung und Differenzialdiagnose
der lymphatischen Fehlfunktion. Die Lymphszintigrafie basiert auf dem (physiologischen)
Transport des Radiotracers und erlaubt eine Beurteilung der Veränderungen des Lymphabflusses
oder Störungen der Lymphgefäße; sie bietet Informationen über den Lymphtransport,
die Filtration und die retikulo-endotheliale Funktion. Klinische Ergebnisse haben
gezeigt, dass die Lymphszintigrafie in Kombination mit der Auswertung mittels numerischen
Transportindex oder mittels Region-of-Interest-Technik gut mit den klinischen Befunden
korreliert und somit suffiziente Aussagen über die Lymphdrainage in der klinischen
Routinediagnostik bietet.
Abstract
Lymphedema usually is diagnosed based on clinical findings, but imaging studies permit
objective confirmation and differential diagnosis of the lymphatic dysfunction. Lymphoscintigraphy
is based on the (physiological) transport of radiotracers and permits the assessment
of changes in lymphatic flow or disturbances of lymphatic vessels; it provides information
about lymph transport, filtration, and reticuloendothelial function. Clinical results
prove that lymphoscintigraphy combined with an evaluation by the numeric transport
index or by means of region-of-interest-technique is well correlated to clinical findings
and therefore provides sufficient information about lymph drainage in routine clinical
diagnostics.
Schlüsselwörter
Lymphszintigrafie - Lymphkinetik - Lymphödem - Lymphabfluss
Key words
lymphoscintigraphy - lymph kinetics - lymph edema - lymph drainage
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Korrespondenzadresse
PD Dr. M. Weiss
Klinik und Poliklinik für Nuklearmedizin
Ludwig-Maximilians-Universität München
Marchioninistr. 15
81377 München
Email: mayo.weiss@med.uni-muenchen.de
