Iodogen: A Novel Reagent for
the Oxidation of Urazoles under Heterogeneous Conditions

Ahmad Khoramabadi-zad; Azam Shiri; Mohammad Ali Zolfigol; Shadpour Mallakpour

doi:10.1055/s-0029-1216902

PAPER

Iodogen: A Novel Reagent for the Oxidation of Urazoles under Heterogeneous Conditions

Ahmad Khoramabadi-zad*^a, Azam Shiri^a, Mohammad Ali Zolfigol^a, Shadpour Mallakpour^b
^a Faculty of Chemistry, Bu-Ali Sina University, P.O. Box 6517838683, Hamadan, Iran
^b Organic Polymer Chemistry Research Laboratory, College of Chemistry, Isfahan University of Technology, Isfahan 84156, Iran
Fax: +98(31)18257407; e-Mail: khoram@basu.ac.ir;

Abstract

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Abstract

Iodogen is employed as an efficient oxidizing agent for the conversion of urazoles and bis-urazoles into the corresponding 1,2,4-triazoles in good to excellent yields under mild heterogeneous conditions at room temperature.

Key words

iodogen - oxidations - chloroamides - glycolurils

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References

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As the product 4-substituted-3H-1,2,4-triazole-3,5-diones are very volatile, it is important that the temperature be maintained below 50 ˚C during evaporation of the solvent to prevent loss of material.