Thorac Cardiovasc Surg 2010; 58: S170-S172
DOI: 10.1055/s-0029-1240711
Originals

© Georg Thieme Verlag KG Stuttgart · New York

Drug Treatment for Chronic Systolic Heart Failure

K. Mörike1 , J. R. Sindermann2
  • 1Institute of Experimental and Clinical Pharmacology and Toxicology, Department of Clinical Pharmacology, University Hospital Tuebingen, Tuebingen, Germany
  • 2Department of Thoracic and Cardiovascular Surgery, University Hospital of Muenster, Muenster, Germany
Further Information

Publication History

Publication Date:
25 January 2010 (online)

Abstract

Drug treatment of chronic systolic heart failure usually includes angiotensin-converting enzyme inhibitor, or an angiotensin II receptor blocker, and a beta blocker, as prognostic benefit of these agents has been demonstrated in a large body of clinical trials. Depending on the stage of the disease and concomitant factors, an aldosterone antagonist and/or a digitalis glycoside may provide additional benefit. Most patients also receive a diuretic for symptomatic relief. Conversely, some drugs may precipitate or aggravate chronic systolic heart failure.

References

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Klaus Mörike, MD

Department of Clinical Pharmacology
Institute of Experimental and Clinical Pharmacology and Toxicology
University Hospital Tuebingen

Otfried-Müller-Straße 45

72076 Tuebingen

Germany

Phone: + 49 7 07 12 97 49 21

Fax: + 49 70 71 29 50 35

Email: klaus.moerike@med.uni-tuebingen.de

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