Dtsch Med Wochenschr 2009; 134: S386-S389
DOI: 10.1055/s-0029-1243047
Übersicht | Review article
Pneumologie
© Georg Thieme Verlag KG Stuttgart · New York

Wechselwirkung zwischen inhalativen Kortikosteroiden und langwirksamen Beta-2-Sympathomimetika

Interaction between inhaled corticosteroids and long-acting beta-2-agonistsP. Kardos1
  • 1Institut Gemeinschaftspraxis und Zentrum für Pneumologie, Allergologie & Schlafmedizin, Klinik Maingau
Further Information

Publication History

eingereicht: 16.2.2009

akzeptiert: 15.10.2009

Publication Date:
25 November 2009 (online)

Literatur

  • 1 Baraniuk J N, Ali M, Brody D. et al . Glucocorticoids induce beta2-adrenergic receptor function in human nasal mucosa.  Am J Respir Crit Care Med. 1997;  155 704-710
  • 2 Barnes P J. Scientific rationale for inhaled combination therapy with long-acting beta2-agonists and corticosteroids.  Eur Respir J. 2002;  19 182-191
  • 3 The Global Initiative for Asthma (GINA) 2008. www.ginasthma.com/Guidelineitem.asp??l1 = 2&l2 = 1&intId = 60. (letzter Zugriff am 2.1.2009. 
  • 4 Greening A P, Ind P W, Northfield M, Shaw G. Added salmeterol versus higher-dose corticosteroid in asthma patients with symptoms on existing inhaled corticosteroid. Allen & Hanburys Limited UK Study Group.  Lancet. 1994;  344 219-224
  • 5 Ichinose M, Takahashi T, Sugiura H. et al . Baseline airway hyperresponsiveness and its reversible component: role of airway inflammation and airway calibre.  Eur Respir J. 2000;  15 248-253
  • 6 Ind P W, Dal Negro R, Colman N C, Fletcher C P, Browning D, James M H. Addition of salmeterol to fluticasone propionate treatment in moderate-to-severe asthma.  Respir Med. 2003;  97 555-562
  • 7 Lakser O J, Dowell M L, Hoyte F L. et al . Steroids augment relengthening of contracted airway smooth muscle: potential additional mechanism of benefit in asthma.  Eur Respir J. 2008;  32 1224-1230
  • 8 Maneechotesuwan K, Essilfie-Quaye S, Meah S. et al . Formoterol attenuates neutrophilic airway inflammation in asthma.  Chest. 2005;  128 1936-1942
  • 9 Pauwels R A, Löfdahl C G, Postma D S. et al . Effect of inhaled formoterol and budesonide on exacerbations of asthma-- Formoterol and Corticosteroids Establishing Therapy (FACET) International Study Group.  N Engl J Med. 1997;  337 1405-1411 , [Erratum appears in N Engl J Med 1998 Jan 8; 338: 139]
  • 10 Roth M, Johnson P R, Rüdiger J J. et al . Interaction between glucocorticoids and beta2 agonists on bronchial airway smooth muscle cells through synchronised cellular signalling.  Lancet. 2002;  360 1293-1299
  • 11 Tulic M K, Christodoulopoulos P, Hamid Q. Small airway inflammation in asthma.  Respir Res. 2001;  2 333-339
  • 12 Usmani O S, Biddiscombe M F, Barnes P J. Regional lung deposition and bronchodilator response as a function of beta2-agonist particle size.  Am J Respir Crit Care Med. 2005;  172 1497-1504
  • 13 Usmani O S, Ito K, Maneechotesuwan K. et al . Glucocorticoid receptor nuclear translocation in airway cells after inhaled combination therapy.  Am J Respir Crit Care Med. 2005;  172 704-712
  • 14 Woolcock A, Lundback B, Ringdal N, Jacques L A. Comparison of addition of salmeterol to inhaled steroids with doubling of the dose of inhaled steroids.  Am J Respir Crit Care Med. 1996;  153 1481-1488

Dr. Peter Kardos

Gemeinschaftspraxis & Zentrum für Pneumologie, Allergologie & Schlafmedizin Klinik Maingau

Scheffelstraße 33

60318 Frankfurt am Main

Phone: 069/553611

Email: pkardos@aol.com

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