Androgen Responses to Sprint Exercise in Young Men

Abstract

The purpose of this study was to investigate the effects of a 6-month sprint training program on plasma androgens and catecholamine (CA) concentrations in response to a 6 s sprint in adolescent boys [training group (TG), n=6; control group (CG), n=6]. A 6 s-sprint test was performed on a cycle ergometer before and after training (Pre-T and Post-T, respectively). Plasma total testosterone (TT), bioavailable testosterone (BT), and CA concentrations were measured at rest, after a warm-up, immediately after a 6 s-sprint, and during the recovery (i. e. 5 and 20 min). After training period, plasma TT concentrations increased significantly at the end of the sprint and during the recovery in the TG. No effects for sampling times and period were observed in BT levels. Plasma TT concentrations after 5 min of recovery were positively correlated with the corresponding values of plasma lactate (La) concentrations and with post-6 s-sprint plasma adrenaline (A) concentrations (r=0.52; p<0.01 and r=0.61; p<0.01, respectively). These results suggest that sprint training increases plasma TT concentrations in response to sprint exercise in adolescent boys. Plasma A and plasma La concentrations increases in response to sprint exercise could be involved in this elevation of plasma TT concentrations.

testosterone - catecholamine - adolescent - sprint training - lactate

References

• 1 Astrand PO, Ryhming I. A nomogram for calculation of aerobic capacity (physical fitness) from pulse rate during sub-maximal work.  J Appl Physiol. 1954;  7 218-221
• 2 Bonifazi M, Bela E, Carli G, Lodi L, Martelli G, Zhu B, Lupo C. Influence of training on the response of androgen plasma concentrations to exercise in swimmers.  Eur J Appl Physiol. 1995;  70 109-114
• 3 Bonifazi M, Lupo C. Differential effects of exercise on sex hormone-binding globulin and non-sex hormone-binding globulin-bound testosterone.  Eur J Appl Physiol. 1996;  72 425-429
• 4 Botcazou M, Jacob C, Gratas-Delamarche A, Vincent S, Bentue-Ferrer D, Delamarche P, Zouhal H. Sex effect on catecholamine responses to sprint exercise in adolescents and adults.  Pediatr Exerc Sci. 2007;  19 132-144
• 5 Brooks BP, Merry DE, Paulson HL, Lieberman AP, Kolson DL, Fischbeck KH. A cell culture model for androgen effects in motor neurons.  J Neurochem. 1998;  70 1054-1060
• 6 Cadoux-Hudson TA, Few JD, Imms FJ. The effect of exercise on the production and clearance of testosterone in well trained young men.  Eur J Appl Physiol. 1985;  54 321-325
• 7 Crewther B, Keogh J, Cronin J, Cook C. Possible stimuli for strength and power adaptation: acute hormonal responses.  Sports Med. 2006;  36 215-238
• 8 Cumming DC, Brunsting 3rd LA, Strich G, Ries AL, Rebar RW. Reproductive hormone increases in response to acute exercise in men.  Med Sci Sports Exerc. 1986;  18 369-373
• 9 Deschenes MR, Kraemer WJ. Performance and physiologic adaptations to resistance training.  Am J Phys Med Rehabil. 2002;  81 S3-S16
• 10 Fahrner CL, Hackney AC. Effects of endurance exercise on free testosterone concentration and the binding affinity of sex hormone binding globulin (SHBG).  Int J Sports Med. 1998;  19 12-15
• 11 Gorostiaga EM, Izquierdo M, Iturralde P, Ruesta M, Ibanez J. Effects of heavy resistance training on maximal and explosive force production, endurance and serum hormones in adolescent handball players.  Eur J Appl Physiol. 1999;  80 485-493
• 12 Gorostiaga EM, Izquierdo M, Ruesta M, Iribarren J, Gonzalez-Badillo JJ, Ibanez J. Strength training effects on physical performance and serum hormones in young soccer players.  Eur J Appl Physiol. 2004;  91 698-707
• 13 Gray AB, Telford RD, Weidemann MJ. Endocrine response to intense interval exercise.  Eur J Appl Physiol. 1993;  66 366-371
• 14 Hansen L, Bangsbo J, Twisk J, Klausen K. Development of muscle strength in relation to training level and testosterone in young male soccer players.  J Appl Physiol. 1999;  87 1141-1147
• 15 Harris DJ, Atkinson G. International Journal of Sports Medicine – Ethical Standards in Sport and Exercise Science Research.  Int J Sports Med. 2009;  30 701-702
• 16 Jezova D, Vigas M, Tatar P, Kvetnansky R, Nazar K, Kaciuba-Uscilko H, Kozlowski S. Plasma testosterone and catecholamine responses to physical exercise of different intensities in men.  Eur J Appl Physiol. 1985;  54 62-66
• 17 Kahn SM, Hryb DJ, Nakhla AM, Romas NA, Rosner W. Sex hormone-binding globulin is synthesized in target cells.  J Endocrinol. 2002;  175 113-120
• 18 Kindermann W, Schnabel A, Schmitt WM, Biro G, Cassens J, Weber F. Catecholamines, growth hormone, cortisol, insulin, and sex hormones in anaerobic and aerobic exercise.  Eur J Appl Physiol. 1982;  49 389-399
• 19 Koubi HE, Desplanches D, Gabrielle C, Cottet-Emard JM, Sempore B, Favier RJ. Exercise endurance and fuel utilization: a reevaluation of the effects of fasting.  J Appl Physiol. 1991;  70 1337-1343
• 20 Kraemer WJ, Ratamess NA. Hormonal responses and adaptations to resistance exercise and training.  Sports Med. 2005;  35 339-361
• 21 Lin H, Wang SW, Wang RY, Wang PS. Stimulatory effect of lactate on testosterone production by rat Leydig cells.  J Cell Biochem. 2001;  83 147-154
• 22 Lu SS, Lau CP, Tung YF, Huang SW, Chen YH, Shih HC, Tsai SC, Lu CC, Wang SW, Chen JJ, Chien EJ, Chien CH, Wang PS. Lactate and the effects of exercise on testosterone secretion: evidence for the involvement of a cAMP-mediated mechanism.  Med Sci Sports Exerc. 1997;  29 1048-1054
• 23 Maestu J, Jurimae J, Jurimae T. Hormonal response to maximal rowing before and after heavy increase in training volume in highly trained male rowers.  J Sports Med Phys Fitness. 2005;  45 121-126
• 24 Mayerhofer A, Bartke A, Began T. Catecholamines stimulate testicular steroidogenesis in vitro in the Siberian hamster, Phodopus sungorus.  Biol Reprod. 1993;  48 883-888
• 25 Mero A, Jaakkola L, Komi PV. Relationships between muscle fibre characteristics and physical performance capacity in trained athletic boys.  J Sports Sci. 1991;  9 161-171
• 26 Morris PD, Malkin CJ, Channer KS, Jones TH. A mathematical comparison of techniques to predict biologically available testosterone in a cohort of 1072 men.  Eur J Endocrinol. 2004;  151 241-249
• 27 Moussa E, Zouhal H, Vincent S, Proiux J, Delamarche P, Gratas-Delamarche A. Effect of sprint duration (6 s or 30 s) on plasma glucose regulation in untrained male subjects.  J Sports Med Phys Fitness. 2003;  43 546-553
• 28 Ramos E, Frontera WR, Llopart A, Feliciano D. Muscle strength and hormonal levels in adolescents: gender related differences.  Int J Sports Med. 1998;  19 526-531
• 29 Slaughter MH, Lohman TG, Boileau RA, Horswill CA, Stillman RJ, Van Loan MD, Bemben DA. Skinfold equations for estimation of body fatness in children and youth.  Hum Biol. 1988;  60 709-723
• 30 Slowinska-Lisowska M, Majda J. Hormone plasma levels from pituitary-gonadal axis in performance athletes after the 400 m run.  J Sports Med Phys Fitness. 2002;  42 243-249
• 31 Sonne B, Mikines KJ, Richter EA, Christensen NJ, Galbo H. Role of liver nerves and adrenal medulla in glucose turnover of running rats.  J Appl Physiol. 1985;  59 1640-1646
• 32 Tanner J. Growth in adolescence. Oxford: Blackwell; 1962
• 33 Tremblay MS, Copeland JL, Van Helder W. Influence of exercise duration on post-exercise steroid hormone responses in trained males.  Eur J Appl Physiol. 2005;  94 505-513
• 34 Tsolakis C, Messinis D, Stergioulas, Dessypris A. Hormonal responses after strength training and detraining in prepubertal and pubertal boys.  J Strength Cond Res. 2000;  16 399-404
• 35 Tsolakis C, Xekouki P, Kaloupsis S, Karas D, Messinis D, Vagenas G, Dessypris A. The influence of exercise on growth hormone and testosterone in prepubertal and early-pubertal boys.  Hormones (Athens). 2003;  2 103-112
• 36 Van Beaumont W, Greenleaf JE, Juhos L. Disproportional changes in hematocrit, plasma volume, and proteins during exercise and bed rest.  J Appl Physiol. 1972;  33 55-61
• 37 Vandewalle H, Peres G, Heller J, Monod H. All out anaerobic capacity tests on cycle ergometers. A comparative study on men and women.  Eur J Appl Physiol. 1985;  54 222-229
• 38 Zouhal H, Jacob C, Delamarche P, Gratas-Delamarche A. Catecholamines and the effects of exercise, training and gender.  Sports Med. 2008;  38 401-423

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