Dtsch Med Wochenschr 2010; 135(24): 1252-1254
DOI: 10.1055/s-0030-1255148
Kommentar | Commentary
Nephrologie
© Georg Thieme Verlag KG Stuttgart · New York

Wann eignet sich Cystatin C zur Bestimmung der Nierenfunktion?

Assessment of renal function with cystatin CR. Woitas1
  • 1Medizinische Klinik u. Poliklinik I, Universitätsklinikum Bonn
Further Information

Publication History

eingereicht: 29.3.2010

akzeptiert: 19.4.2010

Publication Date:
08 June 2010 (online)

Literatur

  • 1 Bjarnadottir M, Grubb A, Olafsson I. Promoter-mediated, dexamethasone-induced increase in cystatin C production by HeLa cells.  Scand J Clin Lab Invest. 1995;  55 617-623
  • 2 Cimerman N, Brguljan P M, Krasovic M. Twenty-four hour variations of cystatin C and total cysteine proteinase inhibitory activity in sera from healthy subjects.  Clin Chim Acta. 2000;  291 89-96
  • 3 Dharnidharka V R, Kwon C, Stevens G. Serum cystatin C is superior to serum creatinine as a marker of kidney function.  Am J Kidney Dis. 2002;  40 221-226
  • 4 Dunn S R, Gabuzda G M, Superdock K R. et al . Induction of creatininase activitiy in chronic renal failure: Timing of creatinine degradation and effect of antibiotics.  Am J Kidney Dis. 1997;  28 72-77
  • 5 Filler G, Lepage N. Should the Schwartz formula for estimation of GFR be replaced by cystatin C formula?.  Pediatr Nephrol. 2003;  18 981-985
  • 6 Finney H, Newmann D J, Price C P. Adult reference ranges for serum cystatin C, creatinine and predicted creatinine clearance.  Ann Clin BIochem. 2000;  37 49-59
  • 7 Fliser D, Ritz E. Serum cystatin C concentration as a marker of renal dysfunction in the elderly.  Am J Kidney Dis. 2001;  37 79-83
  • 8 Fricker M, Wiesli P, Brandle M, Schwegler B, Schmid C. Impact of thyroid dysfunction on serum cystatin C.  Kidney Int. 2003;  63 1944-1947
  • 9 Go A S, Chertow G M, Fan D, McCulloch C E, Hsu C-Y. Chronic kidney disease and the risks of death, cardiovascular events, and hospitalization.  N Engl J Med. 2004;  351 1296-305
  • 10 Hoek, FJ, Kemperman F AW, Krediet R T. A comparison between cystatin C, plasma creatinine and the Cockcroft and Gault formula for the estimation of glomerular filtration rate.  Nephrol Dial Transplant. 2003;  18 2024-2031
  • 11 Jacobsson B, Lignelid H, Bergerheim U S. Transthyretin and cystatin C are catabolized in proximal tubular epithelial cells and the proteins are not useful as markers for renal cell carcinomas.  Histopathology. 1995;  26 559-564
  • 12 K/DOQI clinical practice guidelines for chronic kidney disease: evaluation, classification, and stratification.  Am J Kidney Dis. 2002;  39 S1-266
  • 13 Larsson A, Malm J, Grubb A, Hansson L O. Calculation of glomerular filtration rate expressed in mL/min from plasma cystatin C values in mg/L.  Scand J Clin Lab Invest. 2004;  64 25-30
  • 14 Levey A S, Coresh J, Greene T, Stevens L A, Zhang Y L, Hendriksen S, Kusek J W, Van Lente F. Chronic Kidney Disease Epidemiology Collaboration . Using standardized serum creatinine values in the modification of diet in renal disease study equation for estimating glomerular filtration rate.  Ann Intern Med. 2006;  145 247-254
  • 15 Levey A S, Stevens L A, Schmid C H, Zhang Y L, Castro III A F, Feldman H I, Kusek J W, Eggers P, Van Lente F, Greene T, Coresh J. A new equation to estimate glomerular filtration rate.  Ann Intern Med. 2009;  150 604-612
  • 16 Matsushita K, Selvin E, Bash L D, Astor B C, Coresh J. Risk Implications of the New CKD Epidemiology Collaboration (CKD-EPI) Equation Compared With the MDRD Study Equation for Estimated GFR: The Atherosclerosis Risk in Communities (ARIC) Study.  Am J Kidney Dis. 2010;  55 648-659
  • 17 National Kidney Disease Education Program (NKDEP).  Clin Chem. 2006;  52 5-18
  • 18 Perrone R D, Madias N E, Levey A S. Serum creatinine as an index of renal function: new insights into old concepts.  Clin Chem. 1992;  38 1933-1953
  • 19 Pöge U, Gerhardt T, Stoffel-Wagner B, Palmedo H, Klehr H U, Sauerbruch T, Woitas R P. Cystatin C-based calculation of glomerular filtration rate in kidney transplant recipients.  Kidney Int. 2006;  70 204-210
  • 20 Randers E, Krue S, Erlandsen E J, Danielsen H, Hansen L G. Reference interval for serum cystatin C in children.  Clin Chem. 1999;  45 1856-1858
  • 21 Roos J F, Doust J, Tett S E, Kirkpatrick C M. Diagnostic accuracy of cystatin C compared to serum creatinine for the estimation of renal dysfunction in adults and children.  Clin Biochem. 2007;  40 383-391
  • 22 Rule A D, Bergstralh E J, Slezak J M. et al . Glomerular filtration rate estimated by cystatin C among different clinical presentations.  Kidney Int. 2006;  69 399-405
  • 23 Rule A D. Understanding estimated glomerular filtration rate: implications for identifying chronic kidney disease.  Curr Opin Nephrol Hypertens. 2007;  16 242-249
  • 24 Stevens L A, Coresh J, Schmid C H, Feldman H I, Froissart M, Kusek J, Rossert J, Van Lente F, Bruce 3rd R D, Zhang Y L, Greene T, Levey A S. Estimating GFR using serum cystatin C alone and in combination with serum creatinine.  Am J Kidney Dis. 2008;  51 395-406
  • 25 Stevens L A, Schmid C H, Greene T, Li L, Beck G J, Joffe M M, Froissart M, Kusek J W, Zhang Y L, Coresh J, Levey A S. Factors other than glomerular filtration rate affect serum cystatin C levels.  Kidney Int. 2009;  75 652-660
  • 26 Tenstad O, Roald A B, Grubb A, Aukland K. Renal handling of radiolabelled human cystatin C in the rat.  Scand J Clin Lab Invest. 1996;  56 409-414
  • 27 Uhlmann E J, Hock K G, Issitt C, Sneeringer M R, Cervelli D R, Gorman R T, Scott M G. Reference Intervals for plasma cystatin C in healthy volunteers and renal patients, as measured by the Dade Behring BN II system, and correlation with creatinine.  Clin Chem. 2001;  47 2031-2033
  • 28 Weiner D E, Tighiouart H, Amin M G, Stark P C, MacLeod B, Griffith J L, Salem D N, Levey A S, Sarnak M J. Chronic kidney disease as a risk factor for cardiovascular disease and all-cause mortality.  J Am Soc Nephrol. 2004;  15 1307-1315

Prof. Dr. med. Rainer Woitas

Medizinische Klinik u. Poliklinik I, Universitätsklinikum Bonn

Sigmund-Freudstr. 25

53105 Bonn

Email: woitas@uni-bonn.de

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