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Dtsch Med Wochenschr 2010; 135(38): 1871
DOI: 10.1055/s-0030-1263330
DOI: 10.1055/s-0030-1263330
Pro & Contra | Commentary
Hämatologie, Infektiologie
© Georg Thieme Verlag KG Stuttgart · New York
Pilzprophylaxe bei hämatologischen Patienten: contra
Prophylaxis of fungal infections in haematological patients: contraFurther Information
Publication History
Publication Date:
14 September 2010 (online)
Schlüsselwörter
Pilzinfektionen - Prophylaxe - Neutropenie - Knochenmarktransplantation
Keywords
fungal infections - prophylaxis - neutropenia - bone marrow transplantation
Literatur
- 1 Cornely O A. et al . Posaconazole vs. fluconazole or itraconazole prophylaxis in patients with neutropenia. N Engl J Med. 2007; 356 348-359
- 2 Glasmacher A. et al . Itraconazole prevents invasive fungal infections in neutropenic patients treated for hematologic malignancies: evidence from a meta-analysis of 3,597 patients. J Clin Oncol. 2003; 21 4615-4626
- 3 Marr K A. et al . Itraconazole versus fluconazole for prevention of fungal infections in patients receiving allogeneic stem cell transplants. Blood. 2004; 103 1527-1533
- 4 Marr K A, Laverdiere M, Gugel A, Leisenring W. Antifungal therapy decreases sensitivity of the Aspergillus galactomannan enzyme immunoassay. Clin Infect Dis. 2005; 40 1762-1769
- 5 Marr K A. et al . Prolonged fluconazole prophylaxis is associated with persistent protection against candidiasis-related death in allogeneic marrow transplant recipients. Blood. 2000; 96 2055-2061
- 6 Schaffner A, Frick P G. The effect of ketoconazole on amphotericin B in a model of disseminated aspergillosis. J Infect Dis. 1985; 151 902-910
- 7 Verweij P E, Snelders E, Kema G H, Mellado E, Melchers W J. Azole resistance in Aspergillus fumigatus: a side-effect of environmental fungicide use?. Lancet Infect Dis. 2009; 9 789-795
PD Dr. Stefan Schwartz
Medizinische Klinik III
Charité – Universitätsmedizin
Berlin
Campus Benjamin Franklin
Hindenburgdamm
30
12200 Berlin
Phone: 030/8445-4022
Fax: 030/8445-4468
Email: stefan.schwartz@charite.de