PDF icon Download PDF
Zeitschrift für Phytotherapie 2011; 32(5): 241-246
DOI: 10.1055/s-0031-1271343
Mädesüss
Porträt Einer Arzneipflanze
© Haug Verlag in MVS Medizinverlage Stuttgart GmbH & Co. KG

Mädesüß

 Liselotte Krenn
Further Information

Publication History

Publication Date:
04 November 2011 (online)

   Permissions and Reprints
Preview

Zusammenfassung

Die Blüten und das Kraut von Filipendula ulmaria (L.) Maxim. (Rosaceae; syn. Spirea ulmaria L.) sind Bestandteil der Phytotherapie Europas und werden als schweißtreibendes Mittel bei Erkältungskrankheiten und bei geringfügigen Gelenkschmerzen eingesetzt. Sowohl diese Anwendungen als auch die traditionelle Verwendung als harntreibendes Mittel bzw. bei gastrointestinalen Beschwerden scheinen aufgrund der vorliegenden pharmakologischen Studien plausibel. Die vorliegende Arbeit fasst den Stand der Forschung zu diesen Arzneidrogen zusammen.

Summary

Meadowsweet

The flowers and the aerial parts from Filipendula ulmaria (L.) Maxim. (Rosaceae; syn. Spirea ulmaria L.) are an integral part in European phytotherapy and used as a diaphoretic in common colds and for minor artricular pain. The use in these indications as well as in traditional medicine as a diuretic and in gastrointestinal complaints seems plausible due to the data from pharmacological research. This paper gives an overview over the state of research on Filipendulae ulmariae herba and flos.

Schlüsselwörter

Filipendula ulmaria - Botanik - Inhaltsstoffe - Pharmakologie - Übersicht

Key words

Filipendula ulmaria - botany - chemistry - pharmacology - review

Literatur

  • 1 Adler W. Oswald K. Fischer R. Exkursionsflora von Österreich. Stuttgart, Wien: Eugen Ulmer; 1994
    Search in Google Scholar
  • 2 [Anonymous]. Filipendulae ulmeriae herba – Meadowsweet. ESCOP Monographs. 2nd ed. Exeter: ESCOP; 2003: 157-161
    Search in Google Scholar
  • 3 Avdeeva EY. Krasnov EA. Shilova IV. The composition of fraction from Filipendula ulmaria (L.) Maxim. possess expressed antioxidant activity.  Khimiya Rastitel’nogo Syr’ya. 2008;  (3) 115-118
    Search in Google Scholar
  • 4 Barnaulov OD. Denisenko PP. Antiulcerogenic action of the decoction from flowers of Filipendula ulmaria (L.) Maxim.  Pharmacol Toxicol. 1980;  43 700-705
    Search in Google Scholar
  • 5 Barnaulov OD. Kumkov AV. Khalikova NA. et al.. Rastit Resur. 1977;  13 661-669
    Search in Google Scholar
  • 6 Barnaulov OD. Manicheva OA. Shelyuto Vl. et al.. Effects of flavonoids on the development of experimental gastric dystrophies in mice.  Khim Farm Zh. 1984;  18 935-941
    Search in Google Scholar
  • 7 Bespalov VG. Limarenko AY. Voitenkov BL. Anticarcinogenic, antitumor and modulating activities of dropwort Filipendula ulmaria flower decoction.  Khim Farm Zh. 1992;  26 59-61
    Search in Google Scholar
  • 8 Churin AA. Masnaya NV. Sherstoboev EY. Shilova IV. Effect of Filipendula ulmaria extract on immune system of CBA/CaLac and C57BL/6 mice.  Eksperimental’naya i Klinicheskaya Farmakologiya. 2008;  71 (5) 32-36
    Search in Google Scholar
  • 9 Csedö K. Monea M. Sabău Eşianu S. The antibiotic activity of Filipendula ulmaria .  Planta Med. 1993;  59 (Suppl.) A675
    Search in Google Scholar
  • 10 Cwikla C. Schmidt K. Matthias A. et al.. Investigations into the antibacterial activities of phytotherapeutics against Helicobacter pylori and Campylobacter jejuni.  Phytother Res. 2010;  24 649-656
    Search in Google Scholar
  • 11 Fecka I. Qualitative and quantitative determination of hydrolysable tannins and other polyphenols in herbal products from meadowsweet and dog rose.  Phytochem Anal. 2009;  20 177-190
    Search in Google Scholar
  • 12 Halkes SBA. Beukelman CJ. Kroes BH. et al.. In vitro immunomodulatory activity of Filipendula ulmaria .  Phytother Res. 1997;  11 518-520
    Search in Google Scholar
  • 13 Halkes SBA. Beukelman CJ. Kroes BH. et al.. A strong complement inhibitor from the flowers of Filipendula ulmaria (L.) Maxim.  Pharm Pharmacol Lett. 1997;  7 79-82
    Search in Google Scholar
  • 14 Kähkönen MP. Hopia AI. Vuorela HJ. et al.. Antioxidant activity of plant extracts containing phenolic compounds.  J Agric Food Chem. 1999;  47 3954-3962
    Search in Google Scholar
  • 15 Kazazi F. Halkes SBA. Quarles van Ufford HC. et al.. Inhibition of xanthine oxidase activity by Filipendula species.  Planta Med. 2009;  75 903
    Search in Google Scholar
  • 16 Krasnov EA. Raldugin VA. Avdeeva EY. Medicinal plants – Filimarin, a new flavanol glycoside from Filipendula ulmaria and its antioxidant activity.  Pharm Chem J. 2009;  43 613-614
    Search in Google Scholar
  • 17 Kudryashov BA. et al.. Heparin from Filipendula ulmaria and its properties.  Izv Akad Nauk SSSR, Ser Biol. 1991;  939-943
    Search in Google Scholar
  • 18 Kudryashov BA. Lyapina LA. Aziyeva LD. Heparin-like anticoagulant content in Filipendula ulmaria flowers.  Farmakol Toksikol. 1990;  53 39-41
    Search in Google Scholar
  • 19 Lamaison JL. Carnat A. Petitjean-Freytet C. Teneur en tanins et activité inhibitrice de l’élastase chez les Rosaceae.  Ann Pharm Franç. 1990;  48 335-340
    Search in Google Scholar
  • 20 Lamaison JL. Petitjean-Freytet C. Carnat A. Teneurs en principaux flavonoides de parties aériennes Filipendula ulmaria (L.) Maxim. subsp. ulmaria et subsp. denudata (J. & C: Presl) Hayek.  Pharm Acta Helv. 1992;  67 218-222
    Search in Google Scholar
  • 21 Länger R. Schiller H. Gesundheit aus der Naturapotheke – Richtiger Umgang mit pflanzlichen Arzneimitteln. Wien, New York: Springer; 2004
    Search in Google Scholar
  • 22 Liapina LA. Koval’chuk GA. A comparative study of the action on the hemostatic system of extracts from the flowers and seeds of the meadowsweet (Filipendula ulmaria (L.) Maxim.)  Izvestiia Akademii nauk. Seriia biologicheskaia/Rossiiskaia akademiia nauk. 1993;  ((4)) 625-828
    Search in Google Scholar
  • 23 Lindeman A. Jounela-Eriksson P. Lounasmaa M. The aroma composition of the flower of meadowsweet (Filipendula ulmaria (L.) Maxim.)  Lebensm Wiss Technol. 1982;  15 286-289
    Search in Google Scholar
  • 24 Manicheva OA. Barnaulov OD. Effect of plant drugs on the nucleic acid content of gastric tissues during ulcerogenesis.  Rastit Resur. 1984;  20 256-264
    Search in Google Scholar
  • 25 Mazzio EA. Soliman KF. In vitro screening for the tumoricidal properties of international medicinal herbs.  Phytother Res. 2009;  23 385-398
    Search in Google Scholar
  • 26 McGuffin M Hobbs C Upton R Goldberg A eds. Botanical Safety Handbook. Boca Raton: CRC Press; 1997
    Search in Google Scholar
  • 27 Meier B. Meier-Liebi M Filipendula. In: Blaschek W Ebel S Hackenthal E Holzgrabe U Keller K Reichling J Schulz V Hrsg. Hagers Enzyklopädie der Arzneistoffe und Drogen. 6. Aufl. Bd. 7. Stuttgart: Wiss Verlagsges; 2007
    Search in Google Scholar
  • 28 Mills S. Bone K. Principles and Practice of Phytotherapy. Edinburgh, New York, Toronto: Churchill Livingstone; 2000
    Search in Google Scholar
  • 29 Molokovskii DS. Davydov VV. Khegai MD. Antidiabetic activities of adaptogenic formulations and extns. from medicinal plants.  Rastit Resur. 2002;  38 ((4)) 15-28
    Search in Google Scholar
  • 30 Nesterova IV. Povet’eva TN. Aksinenko SG. et al.. Evaluation of anti-inflammatory activity of extracts from Siberian plants.  Vestnik Rossiiskoi akademii meditsinskikh nauk/Rossiiskaia akademiia meditsinskikh nauk. 2009;  ((11)) 30-34
    Search in Google Scholar
  • 31 Pahlow M. Das große Buch der Arzneipflanzen. München: Gräfe und Unzer; 1987
    Search in Google Scholar
  • 32 Papp I. Apati P. Andrasek V. et al.. LC-MS analysis of antioxidant plant phenoloids.  Chromatographia. 2004;  60 S93-S100
    Search in Google Scholar
  • 33 Pashinskiy VG. Aksinenko SG. Gorbacheva AV. et al.. Pharmacological activity and composition of extract from Filipendula ulmaria underground part.  Rastit Resur. 2006;  42 114-120
    Search in Google Scholar
  • 34 Pawlaczyk I. Czerchawski L. Pilecki W. et al.. Polyphenolic-polysaccharide compounds from selected medicinal plants of Asteraceae and Rosaceae families: Chemical characterization and blood anticoagulant activity.  Carbohydrate Polymers. 2009;  77 568-575
    Search in Google Scholar
  • 35 Peresunko AP. Bespalov VG. Limarenko AI. Aleksandrov VA. Clinico-experimental study of using plant preparations from the flowers of Filipendula ulmaria (L.) Maxim for the treatment of precancerous changes and prevention of uterine cervical cancer.  Vopr Onkol. 1993;  39 291-295
    Search in Google Scholar
  • 36 Proestos C. Boziaris IS. Kapsokefalou M. Komaitis M. Natural antioxidant constituents from selected aromatic plants and their antimicrobial activity against selected pathogenic microorganisms.  Food Technol Biotechnol. 2008;  46 151-156
    Search in Google Scholar
  • 37 Rauha JP. Remes S. Heinonen M. et al.. Antimicrobial effects of Finnish plant extracts containing flavonoids and other phenolic compounds.  Int J Food Microbiol. 2000;  56 3-12
    Search in Google Scholar
  • 38 Šariæ-Kundaliæ B. Dobeš C. Klatte-Asselmeyer V. Saukel J. Ethnobotanical study on medicinal use of wild and cultivated plants in middle, south and west Bosnia and Herzegovina.  J Ethnopharmacol. 2010;  131 33-55
    Search in Google Scholar
  • 39 Schilcher H. Kammerer S. Wegener T. Leitfaden Phytotherapie. 4. Aufl. München: Urban & Fischer; 2010
    Search in Google Scholar
  • 40 Schneider W. Pflanzliche Drogen – Lexikon zur Arzneimittelgeschichte. Frankfurt: Govi; 1974
    Search in Google Scholar
  • 41 Shilova IV. Krasnov EA. Korotkova EI. et al.. Antioxidant properties of extracts from the above-ground parts of Filipendula ulmaria .  Pharm Chem J. 2006;  40 660-662
    Search in Google Scholar
  • 42 Smolarz HD. Sokolowska-Wozniak A. Chromatographic analysis of phenolic acids in Filipendula ulmaria (L.) Maxim and Filipendula hexapetala Gilib.  Chem Environ Res. 2003;  12 77-82
    Search in Google Scholar
  • 43 Spiridonov NA. Konovalov DA. Arkhipov VV. Cytotoxicity of some Russian ethnomedicinal plants and plant compounds.  Phytother Res. 2005;  19 428-432
    Search in Google Scholar
  • 44 Sroka Z. Cisowski W. Seredynska M. Luczkiewicz M. Phenolic extracts from meadowsweet and hawthorn flowers have antioxidative properties.  Z Naturforsch C. 2001;  56 739-744
    Search in Google Scholar
  • 45 Trouillas P. Calliste CA. Allais DP. et al.. Antioxidant, anti-inflammatory and antiproliferative properties of sixteen water plant extracts used in the Limousin countryside as herbal teas.  Food Chem. 2003;  80 399-407
    Search in Google Scholar
  • 46 Tunón H. Olavsdotter C. Bohlin L. Evaluation of anti-inflammatory activity of some Swedish medicinal plants. Inhibition of prostaglandin biosynthesis and PAF-induced exocytosis.  J Ethnopharmacol. 1995;  48 61-76
    Search in Google Scholar
  • 47 Valle MG. Nano GM. Tira S. Das ätherische Öl von Filipendula ulmaria .  Planta Med. 1988;  54 181-182
    Search in Google Scholar
  • 48 Wichtl M. Loew D. Filipendulae ulmaria herba. In: Wichtl M Hrsg. Teedrogen und Phytopharmaka. 5. Aufl.. Stuttgart: Wiss Verlagsges; 2009
    Search in Google Scholar
  • 49 Wilkes S. Glasl H. Isolation, characterization, and systematic significance of 2-pyrone-4,6-dicarboxylic acid in Rosaceae.  Phytochemistry. 2001;  58 441-449
    Search in Google Scholar

Ao. Univ.-Prof. Dr. Liselotte Krenn



Department für Pharmakognosie

Universität Wien

Althanstr. 14

A-1090 Wien

Österreich

Email: liselotte.krenn@univie.ac.at