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Neuropediatrics 2010; 41(6): 264-266
DOI: 10.1055/s-0031-1271658
Short Communications

© Georg Thieme Verlag KG Stuttgart · New York

Postnatal in-vivo MRI findings in Anencephaly

A. Poretti1 , 2 , A. Meoded1 , E. Ceritoglu3 , E. Boltshauser2 , T. A. G. M. Huisman1
  • 1Division of Pediatric Radiology, The Johns Hopkins School of Medicine Baltimore, Maryland, USA
  • 2Division of Pediatric Neurology, University Children's Hospital of Zurich, Zurich, Switzerland
  • 3Division of Neuroradiology, The Johns Hopkins School of Medicine, Baltimore, Maryland, USA
Further Information

Publication History

received 16.11.2010

accepted 04.01.2011

Publication Date:
28 March 2011 (online)

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Corrected by:

Postnatal in-vivo MRI findings in AnencephalyNeuropediatrics 2010; 41(06): e2-e2
DOI: 10.1055/s-0031-1284387

Abstract

We report on the MRI findings of an anencephalic infant who survived 10 weeks postnatally. MRI showed absence of the cranial vault, all supratentorial structures, and the cerebellum. A brainstem primordium without pontine prominence was present. The brainstem was surrounded by the area cerebrovasculosa. The absence of a pontine prominence in an anencephalic infant without cerebellar tissue supports the hypothesis that absent pontine prominence is found in children with a prenatal loss of cerebellar tissue.

Key words

anencephaly - neuroimaging - cerebellum - brainstem - neural tube defects

References

  • 1 Botto LD, Moore CA, Khoury MJ. et al . Neural-tube defects.  N Engl J Med. 1999;  341 1509-1519
    CrossrefPubMedGoogle Scholar
  • 2 Calzolari F, Gambi B, Garani G. et al . Anencephaly: MRI findings and pathogenetic theories.  Pediatr Radiol. 2004;  34 1012-1016
    CrossrefPubMedGoogle Scholar
  • 3 Cox GG, Rosenthal SJ, Holsapple JW. Exencephaly: sonographic findings and radiologic-pathologic correlation.  Radiology. 1985;  155 755-756
    PubMedGoogle Scholar
  • 4 Jaquier M, Klein A, Boltshauser E. Spontaneous pregnancy outcome after prenatal diagnosis of anencephaly.  BJOG. 2006;  113 951-953
    PubMedGoogle Scholar
  • 5 Naidich TP, Altman NR, Braffman BH. et al . Cephaloceles and related malformations.  AJNR Am J Neuroradiol. 1992;  13 655-690
    PubMedGoogle Scholar
  • 6 Nielsen LA, Maroun LL, Broholm H. et al . Neural tube defects and associated anomalies in a fetal and perinatal autopsy series.  APMIS. 2006;  114 239-246
    CrossrefPubMedGoogle Scholar
  • 7 Poretti A, Wolf NI, Boltshauser E. Differential diagnosis of cerebellar atrophy in childhood.  Eur J Paediatr Neurol. 2008;  12 155-167
    CrossrefPubMedGoogle Scholar
  • 8 Poretti A, Prayer D, Boltshauser E. Morphological spectrum of prenatal cerebellar disruptions.  Eur J Paediatr Neurol. 2009;  13 397-407
    CrossrefPubMedGoogle Scholar
  • 9 Timor-Tritsch IE, Greenebaum E, Monteagudo A. et al . Exencephaly-anencephaly sequence: proof by ultrasound imaging and amniotic fluid cytology.  J Matern Fetal Med. 1996;  5 182-185
    CrossrefPubMedGoogle Scholar
  • 10 Tubbs RS, Blount JP. Meroacrania.  Pediatr Neurosurg. 2004;  40 95-96
    CrossrefPubMedGoogle Scholar

Notice:

This article was changed according to the following erratum on: 14.07.2011

The sequence of the authors' names have been changed. The correct order is

A. Poretti, A. Meoded, E. Ceritoglu, E. Boltshauser, T. A. G. M. Huisman

Correspondence

Thierry A. G. M. Huisman

Division of Pediatric Radiology

600 North Wolfe Street

Nelson-Basement

B173

Baltimore

MD 21287

Phone: +410/955/6140

Fax: +410/902/3633

Email: thuisma1@jhmi.edu

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