ABSTRACT
Cervical discogenic pain is an important cause of suffering and disability in the
adult population. Pain management in cervical disc herniation relies initially on
conservative care (rest, physiotherapy, and oral medications). Once conservative treatment
has failed, different percutaneous minimally invasive radiological procedures can
be applied to relief pain. This article offers a systematic review on the percutaneous
minimally invasive techniques that can be advocated for the treatment of cervical
pain of discal origin.
Periradicular steroid injection under image guidance (computed tomography or magnetic
resonance imaging) is the first technique to be considered. The steroid injection
aims at reducing the periradicular inflammation and thus relieves the radicular pain.
The steroid injections present satisfying short-term results, but pain can recur in
the long term.
Whenever the steroid injections fail to relieve pain from a contained cervical disc
herniation, the more invasive percutaneous disc decompression techniques should be
proposed. Percutaneous radiofrequency nucleoplasty is the most often applied technique
on the cervical level with a low risk of thermal damage. When the indications and
instructions are respected, radiofrequency nucleoplasty presents accepted safety and
efficacy levels.
KEYWORDS
Cervical - minimally invasive - disc - CT guidance - radiofrequency nucleoplasty -
infiltrations
REFERENCES
- 1
Castro I, Santos D P, Christoph DdeH, Landeiro J A.
The history of spinal surgery for disc disease: an illustrated timeline.
Arq Neuropsiquiatr.
2005;
63
(3A)
701-706
- 2
Spanu G, Marchionni M, Adinolfi D, Knerich R.
Complications following anterior cervical spine surgery for disc diseases: an analysis
of ten years experience.
Chir Organi Mov.
2005;
90
(3)
229-240
- 3
Gangi A, Dietemann J L, Mortazavi R, Pfleger D, Kauff C, Roy C.
CT-guided interventional procedures for pain management in the lumbosacral spine.
Radiographics.
1998;
18
(3)
621-633
- 4
Andreula C, Muto M, Leonardi M.
Interventional spinal procedures.
Eur J Radiol.
2004;
50
(2)
112-119
- 5
Kobayashi S, Baba H, Uchida K et al..
Effect of mechanical compression on the lumbar nerve root: localization and changes
of intraradicular inflammatory cytokines, nitric oxide, and cyclooxygenase.
Spine (Phila Pa 1976).
2005;
30
(15)
1699-1705
- 6
Kawakami M, Matsumoto T, Kuribayashi K, Tamaki T.
mRNA expression of interleukins, phospholipase A2, and nitric oxide synthase in the
nerve root and dorsal root ganglion induced by autologous nucleus pulposus in the
rat.
J Orthop Res.
1999;
17
(6)
941-946
- 7
Ma D J, Gilula L A, Riew K D.
Complications of fluoroscopically guided extraforaminal cervical nerve blocks. An
analysis of 1036 injections.
J Bone Joint Surg Am.
2005;
87
(5)
1025-1030
- 8
Malhotra G, Abbasi A, Rhee M.
Complications of transforaminal cervical epidural steroid injections.
Spine (Phila Pa 1976).
2009;
34
(7)
731-739
- 9
Huang R C, Shapiro G S, Lim M, Sandhu H S, Lutz G E, Herzog R J.
Cervical epidural abscess after epidural steroid injection.
Spine (Phila Pa 1976).
2004;
29
(1)
E7-E9
- 10
Hooten W M, Kinney M O, Huntoon M A.
Epidural abscess and meningitis after epidural corticosteroid injection.
Mayo Clin Proc.
2004;
79
(5)
682-686
- 11
Yue W M, Tan S B.
Distant skip level discitis and vertebral osteomyelitis after caudal epidural injection:
a case report of a rare complication of epidural injections.
Spine (Phila Pa 1976).
2003;
28
(11)
E209-E211
- 12
Ludwig M A, Burns S P.
Spinal cord infarction following cervical transforaminal epidural injection: a case
report.
Spine (Phila Pa 1976).
2005;
30
(10)
E266-E268
- 13
Rosenkranz M, Grzyska U, Niesen W et al..
Anterior spinal artery syndrome following periradicular cervical nerve root therapy.
J Neurol.
2004;
251
(2)
229-231
- 14
Williams K N, Jackowski A, Evans P JD.
Epidural haematoma requiring surgical decompression following repeated cervical epidural
steroid injections for chronic pain.
Pain.
1990;
42
(2)
197-199
- 15
Reitman C A, Watters III W.
Subdural hematoma after cervical epidural steroid injection.
Spine (Phila Pa 1976).
2002;
27
(6)
E174-E176
- 16
Sandberg D I, Lavyne M H.
Symptomatic spinal epidural lipomatosis after local epidural corticosteroid injections:
case report.
Neurosurgery.
1999;
45
(1)
162-165
- 17
Tok C H, Kaur S, Gangi A.
Symptomatic spinal epidural lipomatosis after a single local epidural steroid injection.
Cardiovasc Intervent Radiol.
2011;
34
(Suppl 2)
S250-S255
- 18
Bush K, Chaudhuri R, Hillier S, Penny J.
The pathomorphologic changes that accompany the resolution of cervical radiculopathy.
A prospective study with repeat magnetic resonance imaging.
Spine (Phila Pa 1976).
1997;
22
(2)
183-186
discussion 187
- 19
McLain R F, Kapural L, Mekhail N A.
Epidural steroid therapy for back and leg pain: mechanisms of action and efficacy.
Spine J.
2005;
5
(2)
191-201
- 20
Cyteval C, Fescquet N, Thomas E, Decoux E, Blotman F, Taourel P.
Predictive factors of efficacy of periradicular corticosteroid injections for lumbar
radiculopathy.
AJNR Am J Neuroradiol.
2006;
27
(5)
978-982
- 21
Stav A, Ovadia L, Sternberg A, Kaadan M, Weksler N.
Cervical epidural steroid injection for cervicobrachialgia.
Acta Anaesthesiol Scand.
1993;
37
(6)
562-566
- 22
Watanabe A T, Nishimura E, Garris J.
Image-guided epidural steroid injections.
Tech Vasc Interv Radiol.
2002;
5
(4)
186-193
- 23
Moreland D B, Asch H L, Clabeaux D E et al..
Anterior cervical discectomy and fusion with implantable titanium cage: initial impressions,
patient outcomes and comparison to fusion with allograft.
Spine J.
2004;
4
(2)
184-191
discussion 191
- 24
Hida K, Iwasaki Y, Yano S, Akino M, Seki T.
Long-term follow-up results in patients with cervical disk disease treated by cervical
anterior fusion using titanium cage implants.
Neurol Med Chir (Tokyo).
2008;
48
(10)
440-446
discussion 446
- 25
Murrey D, Janssen M, Delamarter R et al..
Results of the prospective, randomized, controlled multicenter Food and Drug Administration
investigational device exemption study of the ProDisc-C total disc replacement versus
anterior discectomy and fusion for the treatment of 1-level symptomatic cervical disc
disease.
Spine J.
2009;
9
(4)
275-286
- 26
Alexandre A, Corò L, Azuelos A et al..
Intradiscal injection of oxygen-ozone gas mixture for the treatment of cervical disc
herniations.
Acta Neurochir Suppl (Wien).
2005;
92
79-82
- 27
Buric J, Molino Lova R.
Ozone chemonucleolysis in non-contained lumbar disc herniations: a pilot study with
12 months follow-up.
Acta Neurochir Suppl (Wien).
2005;
92
93-97
- 28
Muto M, Andreula C, Leonardi M.
Treatment of herniated lumbar disc by intradiscal and intraforaminal oxygen-ozone
(O2–O3) injection.
J Neuroradiol.
2004;
31
(3)
183-189
- 29
Riquelme C, Musacchio M, Mont'Alverne F, Tournade A.
Chemonucleolysis of lumbar disc herniation with ethanol.
J Neuroradiol.
2001;
28
(4)
219-229
- 30
Wang J C, Kabo J M, Tsou P M, Halevi L, Shamie A N.
The effect of uniform heating on the biomechanical properties of the intervertebral
disc in a porcine model.
Spine J.
2005;
5
(1)
64-70
- 31
Kotilainen E.
Percutaneous nucleotomy in the treatment of cervical disc herniation: report of three
cases and review.
Minim Invasive Neurosurg.
1999;
42
(3)
152-155
- 32
Courtheoux F, Theron J.
Automated percutaneous nucleotomy in the treatment of cervicobrachial neuralgia due
to disc herniation.
J Neuroradiol.
1992;
19
(3)
211-216
- 33
Nau W H, Diederich C J.
Evaluation of temperature distributions in cadaveric lumbar spine during nucleoplasty.
Phys Med Biol.
2004;
49
(8)
1583-1594
- 34
Chen Y C, Lee S H, Saenz Y, Lehman N L.
Histologic findings of disc, end plate and neural elements after coblation of nucleus
pulposus: an experimental nucleoplasty study.
Spine J.
2003;
3
(6)
466-470
- 35
Lee M S, Cooper G, Lutz G E, Doty S B.
Histologic characterization of coblation nucleoplasty performed on sheep intervertebral
discs.
Pain Physician.
2003;
6
(4)
439-442
- 36
Alexandre A, Corò L, Azuelos A, Pellone M.
Percutaneous nucleoplasty for discoradicular conflict.
Acta Neurochir Suppl (Wien).
2005;
92
83-86
- 37
O'Neill C W, Liu J J, Leibenberg E et al..
Percutaneous plasma decompression alters cytokine expression in injured porcine intervertebral
discs.
Spine J.
2004;
4
(1)
88-98
- 38
Chen Y C, Lee S H, Chen D.
Intradiscal pressure study of percutaneous disc decompression with nucleoplasty in
human cadavers.
Spine (Phila Pa 1976).
2003;
28
(7)
661-665
- 39
Bhagia S M, Slipman C W, Nirschl M et al..
Side effects and complications after percutaneous disc decompression using Coblation
technology.
Am J Phys Med Rehabil.
2006;
85
(1)
6-13
- 40
Chen F, Lü G, Kang Y et al..
Mucormycosis spondylodiscitis after lumbar disc puncture.
Eur Spine J.
2006;
15
(3)
370-376
- 41
Bo W, Longyi C, Jian T et al..
A pyogenic discitis at c3-c4 with associated ventral epidural abscess involving c1-c4
after intradiscal oxygen-ozone chemonucleolysis: a case report.
Spine (Phila Pa 1976).
2009;
34
(8)
E298-E304
- 42
Li J, Yan D L, Zhang Z H.
Percutaneous cervical nucleoplasty in the treatment of cervical disc herniation.
Eur Spine J.
2008;
17
(12)
1664-1669
- 43
Nardi P V, Cabezas D, Cesaroni A.
Percutaneous cervical nucleoplasty using coblation technology. Clinical results in
fifty consecutive cases.
Acta Neurochir Suppl (Wien).
2005;
92
73-78
Afshin GangiM.D. Ph.D.
1 Pl. de l'Hôpital
67000 Strasbourg, France
Email: gangi@rad6.u-strasbg.fr