Können Biologika bei rheumatoider Arthritis nach Erreichen einer Remission abgesetzt werden? Contra

Schlüsselwörter

rheumatoide Arthritis - Biologika - Remission - Erhaltungstherapie

Keywords

rheumatoid arthritis - biologicals - remission - maintenance therapy

Literatur

• 1 Askling J. The risk of malignancies in RA patients treated with biologics.  Z Rheumatol. 2010;  69 774-779
• 2 Braun J, Barraliakos X, Listing J. et al . Persistent clinical efficacy and safety of anti-tumour necrosis factor a therapy with infliximab in patients with ankylosing spondylitis: evidence for different types of response over 5 years.  Ann Rheum Dis. 2008;  67 340-345
• 3 Chatzidionysiou K, van Vollenhoven R F. When to initiate and discontinue biologic treatments for rheumatoid arthritis?.  J Intern Med. 2011;  269 614-625
• 4 Saleem B, Keen H, Goeb V. et al . Patients with RA in remission on TNF blockers: when and in whom can TNF blocker therapy be stopped?.  Ann Rheum Dis. 2010;  69 1636-1642
• 5 van den Broek M, Klarenbeek N B, Dirven L. et al . Discontinuation of infliximab and potential predictors of persistent low disease activity in patients with early rheumatoid arthritis and disease activity score-steered therapy: subanalysis of the BeSt study.  Ann Rheum Dis. 2011;  70 1389-1394