Catheter-Related Infection and Pathogens of Umbilical Venous Catheterization in a Neonatal Intensive Care Unit in China

Ming-Yan Hei; Xiao-Chun Zhang; Xiang-Yu Gao; Ling-Ling Zhao; Zhi-Xiang Wu; Lang Tian; Yan-Juan Tan

doi:10.1055/s-0031-1295650

American Journal of Perinatology, Table of Contents

Am J Perinatol 2012; 29(02): 107-114
DOI: 10.1055/s-0031-1295650

Original Article

Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

Catheter-Related Infection and Pathogens of Umbilical Venous Catheterization in a Neonatal Intensive Care Unit in China

Authors

Ming-Yan Hei

¹Department of Pediatrics, The Third Xiangya Hospital of Central South University, Changsha, Hunan;
Xiao-Chun Zhang

¹Department of Pediatrics, The Third Xiangya Hospital of Central South University, Changsha, Hunan;
Xiang-Yu Gao

²Department of Pediatrics, Affiliated Xuzhou Hospital of East South University, Xuzhou, Jiangsu, People’s Republic of China.
Ling-Ling Zhao

¹Department of Pediatrics, The Third Xiangya Hospital of Central South University, Changsha, Hunan;
Zhi-Xiang Wu

¹Department of Pediatrics, The Third Xiangya Hospital of Central South University, Changsha, Hunan;
Lang Tian

¹Department of Pediatrics, The Third Xiangya Hospital of Central South University, Changsha, Hunan;
Yan-Juan Tan

¹Department of Pediatrics, The Third Xiangya Hospital of Central South University, Changsha, Hunan;

Abstract

We studied the incidence of umbilical venous catheterization (UVC)-related infection and pathogens in a neonatal intensive care unit (NICU) in China. Patients were grouped into <2000-g UVC or <2000-g non-UVC groups or ≥2001-g UVC or ≥2001-g non-UVC groups. Blood culture and umbilical root skin swab culture were taken following UVC insertion and extraction. UVCs were removed after 7 days and cultures of UVC tips were performed then. A total of 516 patients were enrolled. The incidence of UVC-related septicemia was 9.5%. The incidence of UVC-related septicemia per 1000 UVC days was 13.6. No significant difference was noted between <2000-g UVC and <2000-g non-UVC groups and between ≥2001-g UVC group and ≥2001-g non-UVC groups, in the number of positive blood cultures and skin cultures, the percentage of catheter-related septicemia, the incidence of catheter-related septicemia per 1000 catheter days, and the increase in the number of positive cultures between two skin cultures following UVC insertion and extraction. The predominant pathogen in all cultures was gram-positive pathogens. Coagulase-negative Staphylococcus was the most frequently noted pathogen. UVC did not increase the incidence of catheter-related infection in the NICU. It is necessary to consider local pathogen spectrum when choosing antibiotic therapy before specific culture results become available.

Keywords

newborn - umbilical vein - central line - infection - pathogen

Full Text

References

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