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ZWR - Das Deutsche Zahnärzteblatt 2012; 121(01/02): 12-21
DOI: 10.1055/s-0032-1306460
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© Georg Thieme Verlag Stuttgart · New York

Der Einfluss verschiedener Desensitizer auf das De- und Remineralisationsverhalten humanen Dentins

The Influence of Different Desensitizers on the De- and Remineralization of Human Dentine
C R Gernhardt
,
A Francke-Freudenberg
,
A Rother
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Publication Date:
17 February 2012 (online)

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Ziel dieser Untersuchung war es, den Einfluss von 3 verschiedenen Desensitizern (Gluma® Desensitizer, Admira Protect, Hyposen) auf die De- und Remineralisation der Wurzeloberfläche in vitro zu evaluieren.

Die Wurzeloberflächen von 40 frisch extrahierten Weisheitszähnen wurden bis auf 2 Fenster mit einem säureresistenten Nagellack abgedeckt. Alle Zähne wurden randomisiert auf 4 Gruppen verteilt: K: unbehandelte Kontrollgruppe; G: Vorbehandlung mit Gluma® Desensitizer; A: Vorbehandlung mit Admira Protect; H: Vorbehandlung mit Hyposen. Alle Proben wurden 14 Tage lang in angesäuerter Hydroxyethylzellulose (pH 4,8; 37 °C) demineralisiert, und nach Abdeckung einer Hälfte des Testfensters mit einer Natriumfluorid enthaltenden Kalzium-Phosphat-Puffer-Lösung remineralisiert. Aus jedem Testfenster wurde ein Dünnschliff hergestellt und unter dem Polarisationsmikroskop ausgewertet.

In den Desensitizer-Gruppen waren die Läsionstiefen nach Demineralisation im Vergleich zur Kontrollgruppe signifikant reduziert. Der Vergleich von De- und Remineralisation zeigte ebenfalls eine signifikante Reduktion der Läsionstiefe nach Remineralisation in allen Gruppen (p < 0,05, Tukey's Test). Die Remineralisation in den Desensitizer-Gruppen war im Vergleich zur Kontrollgruppe durch die Vorbehandlung jedoch eingeschränkt.

The aim of this study was to evaluate the effect of three different desensitizers (Gluma® Desensitizer, Admira Protect, Hyposen) on the de- and remineralization of root dentine in vitro.

The root surfaces of 40 freshly extracted human third molars were coated with an acid-resistant nail varnish exposing two rectangular windows on the root surface. All teeth were randomly assigned into 4 groups: K: untreated control; G: treated with Gluma® Desensitizer; A: treated with Admira Protect; H: treated with Hyposen. All specimens were demineralized for 14 days with acidified gel (HEC, pH 4.8, 37 °C). Before remineralization using a NaF containing calcium-phosphate buffer solution one half of each window was covered. From each window a dentinal slab was cut. The depth of the demineralized areas was determined using a polarized light microscope.

In the desensitizer-groups the lesion depths were significantly reduced compared to the untreated control. The comparison between de- and remineralized groups showed a significant reduction of lesion depth in all cases (p<0.05, Tukey's test).

It can be concluded that the demineralization of the root surface can be reduced by the application of desensitizing agents. However, the remineralization was limited by the used sealants compared to the control.

Schlüsselwörter

Desensitizer - Demineralisation - Remineralisation - Wurzeldentin

Keywords

Desensitizer - Demineralization - Remineralization - Root Dentine
 

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