Histopathology of Vascular Anomalies

Amir Aboutalebi; Chad J. Jessup; Paula E. North; Martin C. Mihm Jr.

doi:10.1055/s-0032-1329929

Facial Plastic Surgery, Table of Contents

Facial Plast Surg 2012; 28(06): 545-553
DOI: 10.1055/s-0032-1329929

Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

Histopathology of Vascular Anomalies

Amir Aboutalebi

¹Department of Dermatology, Harvard Medical School, Massachusetts General Hospital, Boston, Massachusetts

,

Chad J. Jessup

²Department of Dermatology, Harvard Medical School, Brigham and Women's Hospital, Boston, Massachusetts

,

Paula E. North

³Division of Pediatric Pathology, Department of Pathology and Laboratory Medicine, Children's Hospital of Wisconsin, Medical College of Wisconsin, Milwaukee, Wisconsin

,

Martin C. Mihm Jr.

⁴Department of Dermatology and Pathology, Harvard Medical School, Boston, Massachusetts

⁵Department of Dermatology, Brigham and Women's Hospital, Boston, Massachusetts

› Author Affiliations

Abstract

Vascular anomalies may be appropriately classified into two broad categories, vascular tumors and vascular malformations, which are distinguished by the presence of cellular proliferation in contrast to aberrations in morphogenesis, respectively. This system of classification is based upon histological features that may in large part be differentiating, but nevertheless, may show morphological overlap. Advances in immunophenotyping allow for more precise diagnoses as well as further delineation of cell origins. In the discussion, we present the clinical, histological, and, when applicable, the immunophenotypic presentation of vascular anomalies commonly seen in infancy and early childhood.

Keywords

vascular anomaly - vascular malformation - infantile hemangioma - RICH/NICH - capillary malformation

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References

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