Frauenheilkunde up2date, Table of Contents Frauenheilkunde up2date 2013; 7(5): 363-373DOI: 10.1055/s-0033-1346688 Allgemeine Gynäkologie und gynäkologische Onkologie Georg Thieme Verlag KG Stuttgart · New YorkZielgerichtete Therapien in der Behandlung des Mammakarzinoms Authors Jörg B. Engel Olaf Ortmann Recommend Article Abstract Buy Article(opens in new window) All articles of this category(opens in new window) Full Text References Literatur 1 Baselga J, Bradbury I, Eidtmann H et al. Lapatinib with trastuzumab for HER2-positive early breast cancer (NeoALTTO): a randomised, open-label, multicentre, phase 3 trial. Lancet 2012; 379: 633-640 2 Gianni L, Pienkowski T, Im YH et al. Efficacy and safety of neoadjuvant pertuzumab and trastuzumab in women with locally advanced, inflammatory, or early HER2-positive breast cancer (NeoSphere): a randomised multicentre, open-label, phase 2 trial. Lancet Oncology 2012; 13: 25-32 3 Ismael G, Hegg R, Muehlbauer S et al. 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