Background and study aims: Lesions may be missed during colonoscopy because of anatomical features such as mucosal
folds. This feasibility study assessed the safety and efficacy of a novel colonoscope
with extra-wide angle of view, which provides a simultaneous lateral-backward view
to complement the forward view.
Patients and methods: Consecutive patients undergoing colonoscopy using the prototype colonoscope were
enrolled in this multicenter, single-arm study. The number of adverse events, and
the first detection of adenomas during withdrawal by the lateral-backward view and
the forward view were evaluated.
Results: A total of 47 patients underwent colonoscopy examination to the cecum. The mean insertion
and withdrawal times were 6.4 ± 4.9 minutes and 8.6 ± 4.2 minutes, respectively. Of
47 detected polyps, 28 adenomatous polyps were found (mean size 3.3 ± 3.1 mm). A total
of 29 polyps (61.7 %) and 16 adenomatous polyps (57.1 %) were first detected with
the lateral-backward view. The lateral-backward view first detected 5/6 adenomatous
polyps (83.3 %) in the ascending colon and all (2/2) adenomatous polyps in the sigmoid
colon. No adverse events occurred during the study.
Conclusions: This exploratory study suggested that a novel colonoscope with extra-wide angle of
view is safe and feasible, and has the potential to improve colorectal adenoma detection.
Trial register: UMIN000016450
