TumorDiagnostik & Therapie, Table of Contents TumorDiagnostik & Therapie 2015; 36(07): 398-400DOI: 10.1055/s-0035-1552324 Schwerpunkt: Schilddrüsenkarzinome Georg Thieme Verlag KG Stuttgart · New YorkÜbersicht – Therapie von fortgeschrittenen Schilddrüsenkarzinomen mit Tyrosinkinase-Inhibitoren M. Schott Recommend Article Abstract Buy Article Full Text References Literatur 1 Haq M, Harmer C. Differentiated thyroid carcinoma with distant metastases at presentation: prognostic factors and outcome. Clin Endocrinol 2005; 63: 87-93 2 Brose MS, Nutting CM, Jarzab B et al. Sorafenib in radioactive iodine-refractory, locally advanced or metastatic differentiated thyroid cancer: a randomised, double-blind, phase 3 trial. Lancet 2014; 384: 319-328 3 Schlumberger M, Tahara M, Wirth LJ et al. Lenvatinib versus placebo in radioiodine-refractory thyroid cancer. N Engl J Med 2015; 372: 621-630 4 Elisei R, Romei C, Cosci B et al. RET genetic screening in patients with medullary thyroid cancer and their relatives: experience with 807 individuals at one center. J Clin Endocrinol Metab 2007; 92: 4725-4729 5 Kloos RT, Eng C, Evans DB et al. Medullary thyroid cancer: management guidelines of the American Thyroid Association. Thyroid 2009; 19: 565-612 6 Wells Jr. SA, Robinson BG, Gagel RF et al. Vandetanib in patients with locally advanced or metastatic medullary thyroid cancer: a randomized, double-blind phase III trial. J Clin Oncol 2012; 30: 134-141 7 Elisei R, Schlumberger MJ, Muller SP et al. Cabozantinib in progressive medullary thyroid cancer. J Clin Oncol 2013; 31: 3639-3646