Semin intervent Radiol 2015; 32(03): 272-277
DOI: 10.1055/s-0035-1558466
Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

Predictive Factors for the Development of Type 2 Endoleak Following Endovascular Aneurysm Repair

Paul J. O'Connor
1   Department of Radiology, Icahn School of Medicine at Mount Sinai, New York, New York
,
Robert A. Lookstein
2   Division of Interventional Radiology, Icahn School of Medicine at Mount Sinai, New York, New York
› Author Affiliations
Further Information

Publication History

Publication Date:
18 August 2015 (online)

Abstract

Type 2 endoleak (T2EL) is the most common complication following endovascular aneurysm repair (EVAR) for abdominal aortic aneurysms. The management of T2ELs is controversial due to the relatively low incidence of negative outcomes when secondary intervention is avoided. Some studies challenge this practice as demonstrated by adverse events following conservative treatment of T2ELs. Evidence has shown that the preoperative computed tomographic angiogram can predict the development of T2EL based on a patient's arterial anatomy, specifically vessels associated with increased rates of post-EVAR endoleak development. Preoperative embolization of those aortic branch vessels associated with T2ELs has shown decreased rates of postoperative complications and may result in a decreased need for surveillance and reintervention.

 
  • References

  • 1 Sakalihasan N, Limet R, Defawe OD. Abdominal aortic aneurysm. Lancet 2005; 365 (9470) 1577-1589
  • 2 Hirsch AT, Haskal ZJ, Hertzer NR , et al; American Association for Vascular Surgery; Society for Vascular Surgery; Society for Cardiovascular Angiography and Interventions; Society for Vascular Medicine and Biology; Society of Interventional Radiology; ACC/AHA Task Force on Practice Guidelines; American Association of Cardiovascular and Pulmonary Rehabilitation; National Heart, Lung, and Blood Institute; Society for Vascular Nursing; TransAtlantic Inter-Society Consensus; Vascular Disease Foundation. ACC/AHA 2005 guidelines for the management of patients with peripheral arterial disease (lower extremity, renal, mesenteric, and abdominal aortic): executive summary a collaborative report from the American Association for Vascular Surgery/Society for Vascular Surgery, Society for Cardiovascular Angiography and Interventions, Society for Vascular Medicine and Biology, Society of Interventional Radiology, and the ACC/AHA Task Force on Practice Guidelines (Writing Committee to Develop Guidelines for the Management of Patients With Peripheral Arterial Disease) endorsed by the American Association of Cardiovascular and Pulmonary Rehabilitation; National Heart, Lung, and Blood Institute; Society for Vascular Nursing; TransAtlantic Inter-Society Consensus; and Vascular Disease Foundation. J Am Coll Cardiol 2006; 47 (6) 1239-1312
  • 3 Greenhalgh RM, Brown LC, Kwong GP, Powell JT, Thompson SG ; EVAR trial participants. Comparison of endovascular aneurysm repair with open repair in patients with abdominal aortic aneurysm (EVAR trial 1), 30-day operative mortality results: randomised controlled trial. Lancet 2004; 364 (9437) 843-848
  • 4 Greenhalgh RM, Brown LC, Powell JT, Thompson SG, Epstein D, Sculpher MJ ; United Kingdom EVAR Trial Investigators. Endovascular versus open repair of abdominal aortic aneurysm. N Engl J Med 2010; 362 (20) 1863-1871
  • 5 Lederle FA, Freischlag JA, Kyriakides TC , et al; Open Versus Endovascular Repair (OVER) Veterans Affairs Cooperative Study Group. Outcomes following endovascular vs open repair of abdominal aortic aneurysm: a randomized trial. JAMA 2009; 302 (14) 1535-1542
  • 6 Schanzer A, Greenberg RK, Hevelone N , et al. Predictors of abdominal aortic aneurysm sac enlargement after endovascular repair. Circulation 2011; 123 (24) 2848-2855
  • 7 White GH, Yu W, May J, Chaufour X, Stephen MS. Endoleak as a complication of endoluminal grafting of abdominal aortic aneurysms: classification, incidence, diagnosis, and management. J Endovasc Surg 1997; 4 (2) 152-168
  • 8 Lewin RL, Fatterpekar G, Doshi A, Cohen E, Nowakowski F. Anatomic risk factors for type 2 endoleak following EVAR: a retrospective review of CT angiography in 184 patients. Scientific Abstract presented at: RSNA Annual Meeting; November 27, 2005; Chicago, IL
  • 9 Veith FJ, Baum RA, Ohki T , et al. Nature and significance of endoleaks and endotension: summary of opinions expressed at an international conference. J Vasc Surg 2002; 35 (5) 1029-1035
  • 10 White GH, Yu W, May J. Endoleak—a proposed new terminology to describe incomplete aneurysm exclusion by an endoluminal graft. J Endovasc Surg 1996; 3 (1) 124-125
  • 11 White GH, May J, Waugh RC, Chaufour X, Yu W. Type III and type IV endoleak: toward a complete definition of blood flow in the sac after endoluminal AAA repair. J Endovasc Surg 1998; 5 (4) 305-309
  • 12 Baum RA, Stavropoulos SW, Fairman RM, Carpenter JP. Endoleaks after endovascular repair of abdominal aortic aneurysms. J Vasc Interv Radiol 2003; 14 (9 Pt 1) 1111-1117
  • 13 van Marrewijk C, Buth J, Harris PL, Norgren L, Nevelsteen A, Wyatt MG. Significance of endoleaks after endovascular repair of abdominal aortic aneurysms: The EUROSTAR experience. J Vasc Surg 2002; 35 (3) 461-473
  • 14 Baum RA, Carpenter JP, Tuite CM , et al. Diagnosis and treatment of inferior mesenteric arterial endoleaks after endovascular repair of abdominal aortic aneurysms. Radiology 2000; 215 (2) 409-413
  • 15 Görich J, Rilinger N, Sokiranski R , et al. Leakages after endovascular repair of aortic aneurysms: classification based on findings at CT, angiography, and radiography. Radiology 1999; 213 (3) 767-772
  • 16 Back MR, Bowser AN, Johnson BL, Schmacht D, Zwiebel B, Bandyk DF. Patency of infrarenal aortic side branches determines early aneurysm sac behavior after endovascular repair. Ann Vasc Surg 2003; 17 (1) 27-34
  • 17 van Marrewijk CJ, Fransen G, Laheij RJ, Harris PL, Buth J ; EUROSTAR Collaborators. Is a type II endoleak after EVAR a harbinger of risk? Causes and outcome of open conversion and aneurysm rupture during follow-up. Eur J Vasc Endovasc Surg 2004; 27 (2) 128-137
  • 18 Schlösser FJ, Gusberg RJ, Dardik A , et al. Aneurysm rupture after EVAR: can the ultimate failure be predicted?. Eur J Vasc Endovasc Surg 2009; 37 (1) 15-22
  • 19 Sidloff DA, Stather PW, Choke E, Bown MJ, Sayers RD. Type II endoleak after endovascular aneurysm repair. Br J Surg 2013; 100 (10) 1262-1270
  • 20 Kirkpatrick VE, Wilson SE, Williams RA, Gordon IL. Surveillance computed tomographic arteriogram does not change management before 3 years in patients who have a normal post-EVAR study. Ann Vasc Surg 2014; 28 (4) 831-836
  • 21 Dudeck O, Schnapauff D, Herzog L , et al. Can early computed tomography angiography after endovascular aortic aneurysm repair predict the need for reintervention in patients with type II endoleak?. Cardiovasc Intervent Radiol 2015; 38 (1) 45-52
  • 22 Zhou W, Blay Jr E, Varu V , et al. Outcome and clinical significance of delayed endoleaks after endovascular aneurysm repair. J Vasc Surg 2014; 59 (4) 915-920
  • 23 Ward TJ, Cohen S, Patel RS , et al. Anatomic risk factors for type-2 endoleak following EVAR: a retrospective review of preoperative CT angiography in 326 patients. Cardiovasc Intervent Radiol 2014; 37 (2) 324-328
  • 24 Brountzos E, Karagiannis G, Panagiotou I, Tzavara C, Efstathopoulos E, Kelekis N. Risk factors for the development of persistent type II endoleaks after endovascular repair of infrarenal abdominal aortic aneurysms. Diagn Interv Radiol 2012; 18 (3) 307-313
  • 25 Fukuda T, Matsuda H, Sanda Y , et al. CT Findings of Risk Factors for Persistent Type II Endoleak from Inferior Mesenteric Artery to Determine Indicators of Preoperative IMA Embolization. Ann Vasc Dis 2014; 7 (3) 274-279
  • 26 Ward TJ, Cohen S, Fischman AM , et al. Preoperative inferior mesenteric artery embolization before endovascular aneurysm repair: decreased incidence of type II endoleak and aneurysm sac enlargement with 24-month follow-up. J Vasc Interv Radiol 2013; 24 (1) 49-55
  • 27 Bonvini R, Alerci M, Antonucci F , et al. Preoperative embolization of collateral side branches: a valid means to reduce type II endoleaks after endovascular AAA repair. J Endovasc Ther 2003; 10 (2) 227-232
  • 28 Velazquez OC, Baum RA, Carpenter JP , et al. Relationship between preoperative patency of the inferior mesenteric artery and subsequent occurrence of type II endoleak in patients undergoing endovascular repair of abdominal aortic aneurysms. J Vasc Surg 2000; 32 (4) 777-788
  • 29 Solis MM, Ayerdi J, Babcock GA , et al. Mechanism of failure in the treatment of type II endoleak with percutaneous coil embolization. J Vasc Surg 2002; 36 (3) 485-491
  • 30 Ermis C, Krämer S, Tomczak R , et al. Does successful embolization of endoleaks lead to aneurysm sac shrinkage?. J Endovasc Ther 2000; 7 (6) 441-445
  • 31 Axelrod DJ, Lookstein RA, Guller J , et al. Inferior mesenteric artery embolization before endovascular aneurysm repair: technique and initial results. J Vasc Interv Radiol 2004; 15 (11) 1263-1267