‡ These authors contributed equally to this work
Abstract
A highly efficient copper(II)-catalyzed C–S cross-coupling reaction of aryl iodides
with tetraalkylthiuram disulfides was developed. With only 1 mol% of CuCl2 as catalyst, zinc powder as reductant, and K2CO3 as base, aryl iodides reacted with tetraalkylthiuram disulfides in DMSO furnishing
the corresponding aryl dithiocarbamates in good to excellent yields. This protocol
is an improvement of previous work, it features convenient performance, low addition
of catalyst, no requirement for any ligand, and provides good yields. The method has
a broad substrate scope and uses cheap and readily available starting materials.
Key words
coupling - aryl iodide - disulfide - synthesis - dithiocarbamate
