Prevalence of Protein C Deficiency in Patients with Cardiovascular Problems in Japan

Thromb Haemost 1999; 81(03): 466-467
DOI: 10.1055/s-0037-1614499

Letters to the Editor

Schattauer GmbH

Toshiyuki Sakata

¹From the National Cardiovascular Center, Laboratory of Clinical Chemistry, Suita, Japan

,

Yoshiaki Katayama

¹From the National Cardiovascular Center, Laboratory of Clinical Chemistry, Suita, Japan

,

Tatsuo Matsuyama

¹From the National Cardiovascular Center, Laboratory of Clinical Chemistry, Suita, Japan

,

Hisao Kato

²Research Institute, Fujishirodai, Suita, Japan

,

Toshiyuki Miyata

²Research Institute, Fujishirodai, Suita, Japan

References
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2 Miyata T, Sakata T, Yasumuro Y, Okamura T, Katsumi A, Saito H, Abe T, Shirahata A, Sakai M, Kato H. Genetic analysis of protein C deficiency in nineteen Japanese families: Five recurrent defects can explain half of the deficiencies. Thromb Res 1998; 92: 181-7.
3 Sakata T, Kario K, Katayama Y, Matsuyama T, Kato H, Miyata T. Analysis of 45 episodes of arterial occlusive disease in Japanese patients with congenital protein C deficiency. Thromb Res. 1999 in press.
4 Miletich J, Sherman L, Broze Jr. G. Absence of thrombosis in subjects with heterozygous protein C deficiency. N Engl J Med 1987; 317: 991-6.
5 Tait RC, Isobel D, Walker ID, Reitsma PH, Islam SIAM, McCall F, Poort SR, Conkie JA, Bertina RM. Prevalence of protein C deficiency in the healthy population. Thromb Haemost 1995; 73: 87-93.