Download PDF
Thromb Haemost 1998; 80(05): 864-865
DOI: 10.1055/s-0037-1615376
Letters to the Editor
Schattauer GmbH

Antiphospholipid Syndrome Patients’ Monocytes Are “Primed” to Express Tissue Factor

Frances M. K. Williams
1   From the Lupus Research Unit and Department of Haematology, St. Thomas’ Hospital, London, UK
,
Karen Jurd
1   From the Lupus Research Unit and Department of Haematology, St. Thomas’ Hospital, London, UK
,
Graham R. V. Hughes
1   From the Lupus Research Unit and Department of Haematology, St. Thomas’ Hospital, London, UK
,
Beverley J. Hunt
1   From the Lupus Research Unit and Department of Haematology, St. Thomas’ Hospital, London, UK
› Author Affiliations
Further Information

Publication History

Received 07 May 1998

Accepted after revision 24 July 1998

Publication Date:
07 December 2017 (online)

    Permissions and Reprints

 

 

  • References

  • 1 Arnout J. The pathogenesis of the antiphospholipid syndrome: a hypothesis based on parallelisms with heparin-induced thrombocytopenia. Thromb Haemost 1996; 75 (Suppl. 04) 536-41.
    Article in Thieme ConnectPubMedGoogle Scholar
  • 2 Esmon NL, Smirnov MD, Esmon CT. Thrombogenic mechanisms of anti-phospholipid antibodies. Thromb Haemost 1998; 78 (Suppl. 01) 79-82.
    Article in Thieme ConnectPubMedGoogle Scholar
  • 3 Roubey RAS, Hoffman M. From antiphospholipid syndrome to antibody-mediated thrombosis. Lancet 1998; 350: 1491-3.
    PubMedGoogle Scholar
  • 4 Osterud B, Flaegstad T. Increased tissue thromboplastin activity in monocytes of patients with meningococcal infection: related to an unfavourable prognosis. Thromb Haemost 1983; 49 (Suppl. 01) 5-7.
    Article in Thieme ConnectPubMedGoogle Scholar
  • 5 Leatham EW, P.M.W. B Tooze JA, Camm AJ. Increased monocyte tissue factor expression in coronary disease. Br Heart J 1995; 73: 10-3.
    PubMedGoogle Scholar
  • 6 Semeraro N, Montemurro P, Giordano P, Santoro N, De Mattia D, Colucci M. Increased mononuclear cell tissue factor and type 2 plasminogen activator inhibitor and reduced plasma fibrinolytic capacity in children with lymphoma. Thromb Haemost 1994; 72: 54-7.
    PubMedGoogle Scholar
  • 7 Rosendaal FR. Thrombosis in the young: epidemiology and risk factors. A focus on venous thrombosis. Thromb Haemost 1998; 78 (Suppl. 01) 1-6.
    PubMedGoogle Scholar
  • 8 Amengual O, Atsumi T, Khamashta MA, Hughes GRV. The role of the tissue factor pathway in the hypercoagulable state in patients with the antiphospholipid syndrome. Thromb Haemost 1998; 79: 271-81.
    PubMedGoogle Scholar
  • 9 Altieri DC, Morrissey JH, Edgington TS. Adhesive receptor Mac-1 coordinates the activation of factor X on stimulated cells of monocytic and myeloid differentiation: an alternative initiation of the coagulation protease cascade. Proc Natl Acad Sci USA 1988; 85: 7462-6.
    CrossrefPubMedGoogle Scholar
  • 10 Parratt R, Hunt BJ. Direct activation of factor X by monocytes occurs during cardiopulmonary bypass. Brit J Haematol 1998; 101: 43-6.
    PubMedGoogle Scholar
  • 11 Schved J-F, Gris J-C, Ollivier V, Wautier J-L, Tobelem G, Caen J. Procoagulant activity of endotoxin or tumour necrosis factor activated monocytes is enhanced by IgG from patients with lupus anticoagulant. Am J Hematol 1992; 41: 92-6.
    CrossrefPubMedGoogle Scholar
  • 12 Reverter J-C, Tassies D, Font J. et al. Hypercoagulable state in patients with antiphospholipid syndrome is related to high induced tissue factor expression on monocytes and to low free protein S. Arterioscler Thromb Vasc Biol 1996; 16 (11) 1319-26.
    CrossrefPubMedGoogle Scholar
  • 13 Kornberg A, Blank M, Kaufman S, Shoenfeld Y. Induction of tissue factor-like activity in monocytes by anti-cardiolipin antibodies. J Immunol 1994; 153: 1328-32.
    PubMedGoogle Scholar
  • 14 Cuadrado MJ, Lopez-Pedrera C, Khamashta MA. et al. Thrombosis in primary antiphospholipid syndrome. Arthritis Rheum 1998; 40 (Suppl. 05) 834-41.
    PubMedGoogle Scholar
  • 15 van den Eijinden MM, Steenhauer SI, Reitsma PH, Bertina RM. Tissue Factor expression during monocyte-macrophage differentiation. Thromb Haemost 1998; 77 (Suppl. 06) 1129-36.
    Article in Thieme ConnectPubMedGoogle Scholar
  • 16 Mackman N. Regulation of the tissue factor gene. Thromb Haemost 1998; 78 (Suppl. 01) 747-54.
    Article in Thieme ConnectPubMedGoogle Scholar
  • 17 Rodriquez-Linares B, Watson SP. Thrombopoietin potentiates activation of human platelets in association with JAK2 and TYK2 phosphorylation. Biochem J 1996; 316 (Suppl. 01) 93-8.
    CrossrefPubMedGoogle Scholar