PDF herunterladen
Thromb Haemost 2001; 86(02): 722-723
DOI: 10.1055/s-0037-1616117
Letters to the Editor
Schattauer GmbH

Antithrombin Does not directly Promote the Endothelial Production of Prostacyclin in Cultured Endothelial Cells

Mitsuhiro Uchiba
1   Department of Laboratory Medicine, Kumamoto University School of Medicine, Kumamoto, Japan
,
Kenji Okajima
1   Department of Laboratory Medicine, Kumamoto University School of Medicine, Kumamoto, Japan
› Institutsangaben
Weitere Informationen

Publikationsverlauf

Received 26. Januar 2001

Accepted 23. Februar 2001

Publikationsdatum:
12. Dezember 2017 (online)

Auch verfügbar auf
    Lizenzen und Reprints

 

 

  • References

  • 1 Uchiba M, Okajima K, Murakami K, Okabe H, Takatsuki K. Effects of anti-thrombin III (AT III) and Trp49 modified AT III on plasma levels of 6-ketoPGF1 in rats. Thromb Res 1995; 80: 201-8.
    CrossrefPubMedSuche in Google Scholar
  • 2 Uchiba M, Okajima K, Murakami K, Okabe H, Takatsuki K. Attenuation of endotoxin-induced pulmonary vascular injury by antithrombin III. Am J Physiol 1996; 270: L921-30.
    PubMedSuche in Google Scholar
  • 3 Reisberg B. Antithrombin: facts and new hypotheses. Blood Coagul Fibrinolysis 1998; Suppl (Suppl. 03) S3-6.
    PubMedSuche in Google Scholar
  • 4 Yamaguchi T, Umeda F, Inoguchi T, Nawata H. Antithrombin III stimulates prostacyclin production by cultured aortic endothelial cells. Biochem Biophys Res Commun 1989; 163: 1404-11.
    CrossrefPubMedSuche in Google Scholar
  • 5 Horie S, Ishii H, Kazama M. Heparin-like glycosaminoglycan is a receptor for antithrombin III-dependent but not for thrombin-dependent prostacyclin production in human endothelial cells. Thromb Res 1990; 59: 895-904.
    CrossrefPubMedSuche in Google Scholar
  • 6 Masakado M, Umeda F, Yamauchi T, Ishii H, Ono Y, Nawata H. Human fibroblast cells produce a factor that stimulates prostacyclin synthesis by vascular endothelial cells. Thromb Res 1994; 76: 513-24.
    CrossrefPubMedSuche in Google Scholar
  • 7 Rosenberg RD. Biochemistry of heparin antithrombin interactions, and the physiologic role of this natural anticoagulant mechanism. Am J Med 1989; 87: 2S-9S.
    CrossrefPubMedSuche in Google Scholar