Thrombotic microangiopathies

• References

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• 2 Miyata T, Kawabata S, Iwanaga S. et al. Coagulation factor XII (Hageman factor) Washington D.C. inactive factor XIIa results from Cys-571-Ser substitution. Proc Natl Acad Sci USA 1989; 86: 8319-8322.
• 3 Miyata T, Kokame K, Matsumoto M, Fujimura Y. ADAMTS13 activity and genetic mutations in Japan. Haemostaseologie 2013; 33: 131-137.
• 4 Furlan M. Proteolytic cleavage of von Willebrand factor by ADAMTS-13 prevents uninvited clumping of blood platelets. J Thromb Haemost 2004; 02: 1505-1509.
• 5 Furlan M, Robles R, Lämmle B. Partial purification and characterization of a protease from human plasma cleaving von Willebrand factor to fragments produced by in vivo proteolysis. Blood 1996; 87: 4223-4234.
• 6 Tsai HM. Physiologic cleavage of von Willebrand factor by a plasma protease is dependent on its conformation and requires calcium ion. Blood 1996; 87: 4235-4244.