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Hamostaseologie 2009; 29(S 01): S103-S104
DOI: 10.1055/s-0037-1621504
Communication
Schattauer GmbH

Management of subcutaneous protein C substitution in a child with severe protein C deficiency

Subkutane Protein-C-Substitution bei einem Kind mit schwerem Protein-C-Mangel
M. Olivieri
1   Department of Paediatric Haemostaseology, Dr. von Haunersches Children‘s Hospital, LMU Munich
,
K. Kurnik
1   Department of Paediatric Haemostaseology, Dr. von Haunersches Children‘s Hospital, LMU Munich
,
I. Engelsberger
2   Department of Neonatology, Children‘s Hospital Schwabing, TU Munich
,
C. Bidlingmaier
1   Department of Paediatric Haemostaseology, Dr. von Haunersches Children‘s Hospital, LMU Munich
› Author Affiliations
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Publication History

Publication Date:
04 January 2018 (online)

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  • Literatur

  • 1 Marlar RA, Mastovich S. Hereditary protein C deficiency: a review of the genetics, clinical presentation, diagnosis and treatment. Blood Coagul Fibrinolysis 1990; 1: 319-330.
    CrossrefPubMedGoogle Scholar
  • 2 Bauer KA. Protein C deficiency. www.uptodate.com
    PubMedGoogle Scholar
  • 3 Reitsma PH, Poort SR, Bernardi F. et al. Protein C deficiency: a database of mutations. For the Protein C & S Subcommittee of the Scientific and Standardization Committee of the International Society on Thrombosis and Haemostasis. Thromb Haemost 1993; 69: 77-84.
    Article in Thieme ConnectPubMedGoogle Scholar
  • 4 Knoebl PN. Human protein C concentrates for replacement therapy in congenital and acquired protein C deficiency. Drugs Today (Barc) 2008; 44: 429-441.
    CrossrefPubMedGoogle Scholar
  • 5 Dreyfus M, Masterson M, David M. et al. Replacement therapy with a monoclonal antibody purified protein c concentrate in newborns with severe congenital protein c defieciency. Semin Thromb He-most 1995; 21: 371-381.
    Article in Thieme ConnectPubMedGoogle Scholar
  • 6 Mathias M, Khair K, Burgess C, Liesner R. Subcutaneous administration of protein c concentrate. Pediatr Hematol Oncol 2004; 21: 551-556.
    PubMedGoogle Scholar
  • 7 Sanz-Rodriguez C. et al. Long-term management of homozygous protein C deficiency: Replacement therapy with subcutaneous purified protein c concentrate. Thromb Haemost 1999; 81: 887-890.
    Article in Thieme ConnectPubMedGoogle Scholar
  • 8 Monagle P, Newall F, Ignjatovic V. et al. Homozygous protein c deficiency: subcutaneous protein c replacement is effective as salvage or maintenance therapy?. Blood 2002; 100: 267a.
    PubMedGoogle Scholar
  • 9 Fernandez-Burriel M. et al. Severe clinical presentation of protein C deficiency in a type I/II compound heterozygote newborn. Thromb Haemost 2005; 94: 216-218.
    Article in Thieme ConnectPubMedGoogle Scholar
  • 10 Minford AM, Parapia LA, Stainforth C, Lee D. Treatment of homozygous protein C deficiency with subcutaneous protein C concentrate. Br J Haematol 1996; 93: 215-216.
    CrossrefPubMedGoogle Scholar