Substrate specificity of vitamin K epoxide reductase C1

Hamostaseologie 2009; 29(S 01): S116
DOI: 10.1055/s-0037-1621505

Communication

Schattauer GmbH

Substratspezifität der Vitamin-K-Epoxid-reduktase C1

M. Marinova

¹Institute of Experimental Haematology and Transfusion Medicine, University Clinic Bonn, Germany

,

M. Watzka

¹Institute of Experimental Haematology and Transfusion Medicine, University Clinic Bonn, Germany

,

P. Westhofen

¹Institute of Experimental Haematology and Transfusion Medicine, University Clinic Bonn, Germany

,

M. Hass

¹Institute of Experimental Haematology and Transfusion Medicine, University Clinic Bonn, Germany

,

D. Lütjohann

²Institute of Clinical Biochemistry and Pharmacology, University Clinic Bonn, Germany

,

J. Oldenburg

¹Institute of Experimental Haematology and Transfusion Medicine, University Clinic Bonn, Germany

References
1 Rost S, Fregin A, Ivaskevicius V. et al. Mutations in VKORC1 cause warfarin resistance and multiple coagulation factor deficiency type 2. Nature 2004; 427 6974 537-541.
2 Oldenburg J, Bevans CG, Müller CR, Watzka M. Vitamin K epoxide reductase complex subunit 1 (VKORC1): the key protein of the vitamin K cycle. Antioxid Redox Signal 2006; 8: 347-353.