First Experiments on Radioimmunodetection with b-12-Monoclonal Antibody Fragments against Breast Cancer Antigen

R. Fridrich; R. Andres; C. Stähli; H. R. Zenklusen

doi:10.1055/s-0038-1624347

Nuklearmedizin - NuclearMedicine, Table of Contents

Nuklearmedizin 1986; 25(06): 225-226
DOI: 10.1055/s-0038-1624347

Originalarbeiten — Original Articles

Schattauer GmbH

First Experiments on Radioimmunodetection with b-12-Monoclonal Antibody Fragments against Breast Cancer Antigen^[*]

R. Fridrich

¹From the Department of Nuclear Medicine, University Hospital Basel, Switzerland

,

R. Andres

¹From the Department of Nuclear Medicine, University Hospital Basel, Switzerland

,

C. Stähli

¹From the Department of Nuclear Medicine, University Hospital Basel, Switzerland

,

H. R. Zenklusen

¹From the Department of Nuclear Medicine, University Hospital Basel, Switzerland

› Author Affiliations

Abstract

In 14 patients with breast cancer the results of radioimmunoscintigraphy with ¹²³l-labeled b-12 monoclonal antibody fragments were correct in more than two thirds of the patients.

Zusammenfassung

Bei 14 Patienten mit Mammakarzinom zeigte die Radioimmunszintigraphie mit ¹²³J markierten b-12 monoklonalen Antikörperfragmenten bei über zwei Drittel aller Patienten ein richtiges Ergebnis.

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References

REFERENCES
1 Bradwell A, Fairweather D, Dylles P, Keeling A. Limiting factors in the localization of tumours with radiolabeled antibodies. Immunology Today 1985; 06: 163-70.
2 Stähli C, Takacs B, Miggiano V, Staehelin T, Carmann H. Monoclonal antibodies against antigens on breast cancer cells. Experientia 1985; 41: 1377-81.

First Experiments on Radioimmunodetection with b-12-Monoclonal Antibody Fragments against Breast Cancer Antigen[*]

First Experiments on Radioimmunodetection with b-12-Monoclonal Antibody Fragments against Breast Cancer Antigen^[*]