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Nuklearmedizin 1974; 13(02): 151-159
DOI: 10.1055/s-0038-1624852
Originalarbeiten — Original Articles
Schattauer GmbH

67Ga-Citrate Accumulation by Staphylococcal Abscesses and by Tumors

A Common Cause: Changes in the Alkaline-Earths Metabolism 67Ga-Zitrat-Speicherung in Staphylokokkenabszessen und in TumorenEine gemeinsame Ursache: Veränderungen im Stoffwechsel der Erdalkalien
Leopoldo J. Anghileri   *
1   Aus der Inneren Klinik und Poliklinik (Tumorforscbung) des Klinikum der Gesamthochschule Essen (Direktor: Prof. Dr. C. G. Schmidt)
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Publication History

Received:07 November 1973

Publication Date:
12 January 2018 (online)

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Summary

The in vivo uptake of 67Ga-citrate by staphylococcal abscesses in rats has been studied. The high accumulation of calcium and magnesium in the abscess and in the surrounding tissues appears to be responsible for the accumulation of 67Ga. The role of the mast cells in the inflammatory process which leads to a calcification (calciphylaxis) is discussed and related to their possible involvement in the case of tumor transplants.

Die in-vivo-Aufnahme von 67 Ga-Zitrat in Staphylokokken-Abszessen bei Ratten wurde untersucht. Die hohe Anreicherung von Kalzium und Magnesium in dem Abszeß und in den umgebenden Geweben scheint für die Anreicherung von 67Ga verantwortlich zu sein. Die Rolle der Mastzellen in dem Entzündungsprozeß, der zur Ratifizierung (Kalziphylaxie) führt , wird diskutiert und mit ihrer möglichen Beteiligung im Falle von Tumortransplantaten in Beziehung gebracht.

* This work has been partially supported by the Ministerium für Wissenschaft und Forschung des Landes Nordrhein-Westfalen.


 

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