Transkranielle Magnetstimulation und bildgebende Verfahren des ZNS

Zusammenfassung

Die transkranielle Magnetstimulation (TMS), ein etabliertes diagnostisches Verfahren in der Neurologie, kristallisiert sich derzeit als eine viel versprechende Behandlungsstrategie in der Psychiatrie heraus. In Kombination mit bildgebenden Verfahren wie PET, SPECT und (f)MRT liefert die TMS neuartige Kenntnisse in die Organisation neuronaler Netzwerke. Die Ergebnisse bieten Einblick in die Wirkungsweise der TMS, geben Aufschluss über die Optimierung der Stimulationsspulenplatzierung und vertiefen das Verständnis neurofunktioneller und -anatomischer Zusammenhänge. Die vorliegende Arbeit versucht einen aktuellen Überblick der Ergebnisse aus dem Gebiet der TMS in Kombination mit bildgebenden Verfahren zu geben.

Summary

Transcranial magnetic stimulation (TMS) is a still new and promising field in neuropsychiatry. Combined with neuroimaging methods, such as PET, SPECT, and (f)MRI TMS provides the opportunity to analyze neuronal networks and delivers new insights into the yet not understood functioning of the brain. Thus, the integration of different imaging strategies and TMS offers more information on basic and therapeutic effects of TMS in the brain, enlightens the mechanism also of previous functional neuroimaging results and gives the possibility to deal with the controversial discussed topic of the optimal coil placement. In this paper we present an overview of this intriguing and rapidly advancing field.

Schlüsselwörter

Transkranielle Magnetstimulation - PET - SPECT - Nahinfrarotspektroskopie - MRT - EEG

Keywords

Transcranial magnetic stimulation - PET - SPECT - near-infrared spectroscopy - MRI - EEG

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