Nervenheilkunde 2011; 30(04): 239-244
DOI: 10.1055/s-0038-1627803
Schizophrenie
Schattauer GmbH

Wenn Antipsychotika nicht helfen

Kognitiv-verhaltenstherapeutische Interventionen bei persistierendem Wahn und chronischem StimmenhörenIf antipsychotic drugs are not sufficient
R. Vauth
1   Psychiatrische Universitätspoliklinik, Universitäre Psychiatrische Kliniken Basel
› Author Affiliations
Further Information

Publication History

Eingegangen am: 30 June 2010

angenommen am: 08 October 2010

Publication Date:
23 January 2018 (online)

Zusammenfassung

Mehr als 20% aller Patienten mit einer schizophrenen Störung weisen trotz optimierter Pharmakotherapie und Compliance mehr oder weniger ausgeprägte chronische Positivsymptomatik auf. Kognitive Verhaltenstherapie liefert problemspezifische und gut evaluierte, weiterentwickelte einzel- und gruppentherapeutische Ansätze, die der Hälfte der Patienten helfen können, im Alltag besser zurecht zu kommen. In der Praxis haben sie immer noch eine viel zu geringe Verbreitung gefunden, obwohl Institutsambulanzen und Polikliniken sowohl verhaltenstherapeutisch ausgebildete Ärzte und Psychologen aufweisen und Mitarbeiter aus der Pflege entsprechend trainiert werden können.

Summary

In spite of optimized antipsychotic drug treatment and compliance more than 20% of people with schizophrenia are disabled in their every day behaviour and role functioning by persistent delusions and voices. A growing body of research demonstrated efficacy of cognitive-behavioural treatment and help for more than 50% of treated patients. But in routine care only supportive treatment strategies are well delivered and only a small proportion of patients are provided with these treatment strategies. So the resource utilization of community treatment centres is not well developed so far.

 
  • Literatur

  • 1 Appelbaum PS, Robbins PC, Vesselinov R. Persistence and stability of delusions over time. Compr Psychiatry 2004; 45 (05) 317-24.
  • 2 Ascher-Svanum H. et al. Medication adherence and long-term functional outcomes in the treatment of schizophrenia in usual care. J Clin Psychiatry 2006; 67 (03) 453-60.
  • 3 Assion HJ. et al. Amisulpride augmentation in patients with schizophrenia partially responsive or unresponsive to clozapine. A randomized, doubleblind, placebo-controlled trial. Pharmacopsychiatry 2008; 41 (01) 24-8.
  • 4 Beck AT, Rector NA. Cognitive approaches to schizophrenia: theory and therapy. Annu Rev Clin Psychol 2005; 600-6.
  • 5 Chan J, Sweeting M. Review: Combination therapy with non-clozapine atypical antipsychotic medication: a review of current evidence. J Psychopharmacol 2007; 21 (06) 657-64.
  • 6 Cormac I, Jones C, Campbell C. Cognitive behaviour therapy for schizophrenia. Cochrane Database Syst Rev 2002; 01: CD000524.
  • 7 Farhall J. et al. Coping with hallucinated voices in schizophrenia: a review of self-initiated strategies and therapeutic interventions. Clin Psychol Rev 2007; 27 (04) 476-93.
  • 8 Garety PA. et al. Implications for neurobiological research of cognitive models of psychosis: a theoretical paper. Psychol Med 2007; 37 (10) 1377-91.
  • 9 Garety PA. et al. Cognitive-behavioral therapy for medication-resistant symptoms. Schizophrenia Bulletin 2000; 26 (01) 73-86.
  • 10 Garety PA. et al. Reasoning, emotions, and delusional conviction in psychosis. Journal of Abnormal Psychology 2005; 114 (03) 373-84.
  • 11 Harrow M. et al. Followup of psychotic outpatients: dimensions of delusions and work functioning in schizophrenia. Schizophrenia Bulletin 2004; 30 (01) 147-61.
  • 12 Jones C. et al. Cognitive behaviour therapy for schizophrenia. Cochrane Database Syst Rev 2004; 04: CD000524.
  • 13 Karunakaran K. et al. Is clozapine-aripiprazole combination a useful regime in the management of treatment-resistant schizophrenia?. J Psychopharmacol 2007; 21 (04) 453-6.
  • 14 Lincoln TM. Kognitive Verhaltenstherapie der Schizophrenie. Göttingen: Hogrefe; 2006
  • 15 Newton E. et al. Early psychological intervention for auditory hallucinations: an exploratory study of young people’s voices groups. J Nerv Ment Dis 2005; 193 (01) 58-61.
  • 16 Olbrich HM. et al. Schizophrenie und andere psychotische Störungen. In: Berger M. (Ed.). Psychische Erkrankungen. Klinik und Therapie. München: Urban und Fischer; 2009
  • 17 Penn DL. et al. A randomized controlled trial of group cognitive-behavioral therapy vs. enhanced supportive therapy for auditory hallucinations. Schizophrenia Research 2009; 109: 52-9.
  • 18 Penn DL. et al. Psychosocial treatment for first-episode psychosis: a research update. American Journal of Psychiatry 2005; 162 (12) 2220-32.
  • 19 Pilling S. et al. Psychological treatments in schizophrenia: II. Meta-analyses of randomized controlled trials of social skills training and cognitive remediation. Psychol Med 2002; 32 (05) 783-91.
  • 20 Rathod S, Phiri P, Kingdon D. Cognitive behavioral therapy for schizophrenia. Psychiatr Clin North Am 2010; 33 (03) 527-36.
  • 21 Rector NA, Beck AT. Cognitive therapy for schizophrenia: from conceptualization to intervention. Can J Psychiatry 2002; 47 (01) 39-48.
  • 22 Remington G. et al. Augmentation strategies in clozapine-resistant schizophrenia. Cns Drugs 2005; 19 (10) 843-72.
  • 23 van der Gaag M. A neuropsychiatric model of biological and psychological processes in the remission of delusions and auditory hallucinations. Schizophrenia Bulletin 2006; 32 Suppl 1: S113-S122.
  • 24 Vauth R. Die umfassende Bedeutung schizophrener Störungen als klinische Herausforderung. In: Strauss B, Hohagen F, Caspar F. (Eds.). Lehrbuch Psychotherapie. Teilband 1. Göttingen: Hogrefe; 2007
  • 25 Vauth R, Stieglitz RD. Chronische Stimmenhören und persistierender Wahn. Fortschritte der Psychotherapie. Göttingen: Hogrefe; 2007
  • 26 Wykes T. et al. What are the effects of group cognitive behaviour therapy for voices? A randomised control trial. Schizophr Res 2005; 77 (2–3): 201-10.
  • 27 Wykes TS. et al. Cognitive behavior therapy for schizophrenia: effect sizes, clinical models, and methodological rigor. Schizophrenia Bulletin 2008; 34: 523-37.