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DOI: 10.1055/s-0038-1639844
The reliability of F18-FDG-PET/CT in tumordiagnostics of Head-and-Neck squamous-cell carcinoma
Introduction:
F18-FDG-PET/CT plays an important role in tumor-staging of Head-and-Neck squamous-cell carcinoma. It gives the possibility to detect primary tumors and local and distant metastasis. Some studies have found a sensivity of up to 96% for PET/CT. Other have assessed a lower sensivity. Aim of this study was to compare the results of preoperative PET/CT with the histopathology results.
Methods:
In this restrospective study 11 patients (Age 53 to 82 years) had been examined. They were examined with PET/CT because of high suspicion of having a Head-and-Neck squamous-cell carcinoma. The results of PET/CT were compared with the histopathology results.
Results:
All subjects had positive findings of suspicious lymph-nodes in PET/CT. After surgery in 4 subjects no malignancy could be found in the histopathology results. In 7 subjects metastasis in lymph nodes were found.
Conclusion:
All activities in PET/CT have always to be evaluated with possible differential diagnosis. Further investigations is needed to evaluate how good the relieability of PET/CT results are, especially towards negative results and towards micrometastasis in lymph nodes. More patients will be included in this study.
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No conflict of interest has been declared by the author(s).
Publication History
Publication Date:
18 April 2018 (online)
© 2018. The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial-License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/).
Georg Thieme Verlag KG
Stuttgart · New York