J Neurol Surg A Cent Eur Neurosurg 2018; 79(05): 372-379
DOI: 10.1055/s-0038-1646958
Original Article
Georg Thieme Verlag KG Stuttgart · New York

Atlantoaxial Instability in Patients Older Than 70 Years: What Is the Outcome When Further Conservative Treatment Is Not an Option?

Christoph Scholz
1   Department of Neurosurgery, Medical Center, Faculty of Medicine, University of Freiburg, Freiburg, Germany
,
Jan-Helge Klingler
1   Department of Neurosurgery, Medical Center, Faculty of Medicine, University of Freiburg, Freiburg, Germany
,
Christian Scheiwe
1   Department of Neurosurgery, Medical Center, Faculty of Medicine, University of Freiburg, Freiburg, Germany
,
Yashar Naseri
1   Department of Neurosurgery, Medical Center, Faculty of Medicine, University of Freiburg, Freiburg, Germany
,
Waseem Masalha
1   Department of Neurosurgery, Medical Center, Faculty of Medicine, University of Freiburg, Freiburg, Germany
,
UIrich Hubbe
1   Department of Neurosurgery, Medical Center, Faculty of Medicine, University of Freiburg, Freiburg, Germany
› Author Affiliations
Further Information

Publication History

01 September 2017

08 February 2018

Publication Date:
04 July 2018 (online)

Abstract

Objective We report on our experiences of navigated posterior C1–C2 spondylodesis in the elderly (≥ 70 years of age).

Patients This retrospective cohort study evaluated all patients ≥ 70 years of age treated with navigated posterior spondylodesis C1-C2 (at the most to C3) from 2008 to 2015 with a minimum follow-up of 1 year. Minor and major complications within 30 days after surgery, patient outcome, and the rate of solid fusion in computed tomography were recorded. The follow-up over 1 year was conducted by outpatient examinations and via telephone interviews.

Results Twenty-two patients with a mean age of 79.9 years (range: 71–91 years) were treated. Minor complications were mild pneumonia (18.2%), postoperative confusion (9.1%), and urinary tract infection (4.5%). Major complications were severe pneumonia (4.5%) and clinically asymptomatic vertebral artery injury (4.5%). The mortality rate was 13.6% (n = 3) within the first 30 days after surgery and 22.7% (n = 5) within 1 year. All deceased patients were > 85 years of age.

Conclusion In our patient population, posterior spondylodesis was shown to be beneficial for patients > 70 years up to age ∼ 85 years. The mortality rate increased sharply in patients > 85 years. In these patients the indication for surgery should be critically evaluated.

 
  • References

  • 1 Elliott RE, Tanweer O, Boah A. , et al. Atlantoaxial fusion with transarticular screws: meta-analysis and review of the literature. World Neurosurg 2013; 80 (05) 627-641
  • 2 Elliott RE, Tanweer O, Boah A. , et al. Atlantoaxial fusion with screw-rod constructs: meta-analysis and review of literature. World Neurosurg 2014; 81 (02) 411-421
  • 3 Watanabe M, Sakai D, Yamamoto Y, Sato M, Mochida J. Upper cervical spine injuries: age-specific clinical features. J Orthop Sci 2010; 15 (04) 485-492
  • 4 Schoenfeld AJ, Bono CM, Reichmann WM. , et al. Type II odontoid fractures of the cervical spine: do treatment type and medical comorbidities affect mortality in elderly patients?. Spine 2011; 36 (11) 879-885
  • 5 White AP, Hashimoto R, Norvell DC, Vaccaro AR. Morbidity and mortality related to odontoid fracture surgery in the elderly population. Spine 2010; 35 (9, Suppl): S146-S157
  • 6 Chen Y-R, Boakye M, Arrigo RT. , et al. Morbidity and mortality of C2 fractures in the elderly: surgery and conservative treatment. Neurosurgery 2012; 70 (05) 1055-1059 ; discussion 1059
  • 7 Frangen TM, Zilkens C, Muhr G, Schinkel C. Odontoid fractures in the elderly: dorsal C1/C2 fusion is superior to halo-vest immobilization. J Trauma 2007; 63 (01) 83-89
  • 8 Molinari RW, Dahl J, Gruhn WL, Molinari WJ. Functional outcomes, morbidity, mortality, and fracture healing in 26 consecutive geriatric odontoid fracture patients treated with posterior fusion. J Spinal Disord Tech 2013; 26 (03) 119-126
  • 9 Magerl F, Seemann P-S. Stable posterior fusion of the atlas and axis by transarticular screw fixation. In: Kehr P, Weidner A. , eds. Cervical Spine I. Vienna, Austria: Springer; 1987: 322-327
  • 10 Harms J, Melcher RP. Posterior C1-C2 fusion with polyaxial screw and rod fixation. Spine 2001; 26 (22) 2467-2471
  • 11 Gertzbein SD, Robbins SE. Accuracy of pedicular screw placement in vivo. Spine 1990; 15 (01) 11-14
  • 12 Harris MB, Reichmann WM, Bono CM. , et al. Mortality in elderly patients after cervical spine fractures. J Bone Joint Surg Am 2010; 92 (03) 567-574
  • 13 Harrop JS, Hart R, Anderson PA. Optimal treatment for odontoid fractures in the elderly. Spine 2010; 35 (21, Suppl): S219-S227
  • 14 Vaccaro AR, Kepler CK, Kopjar B. , et al. Functional and quality-of-life outcomes in geriatric patients with type-II dens fracture. J Bone Joint Surg Am 2013; 95 (08) 729-735
  • 15 Ryang Y-M, Török E, Janssen I. , et al. Early morbidity and mortality in 50 very elderly patients after posterior atlantoaxial fusion for traumatic odontoid fractures. World Neurosurg 2016; 87: 381-391
  • 16 Delcourt T, Bégué T, Saintyves G, Mebtouche N, Cottin P. Management of upper cervical spine fractures in elderly patients: current trends and outcomes. Injury 2015; 46 (Suppl. 01) S24-S27
  • 17 Koech F, Ackland HM, Varma DK, Williamson OD, Malham GM. Nonoperative management of type II odontoid fractures in the elderly. Spine 2008; 33 (26) 2881-2886
  • 18 Tashjian RZ, Majercik S, Biffl WL, Palumbo MA, Cioffi WG. Halo-vest immobilization increases early morbidity and mortality in elderly odontoid fractures. J Trauma 2006; 60 (01) 199-203
  • 19 Majercik S, Tashjian RZ, Biffl WL, Harrington DT, Cioffi WG. Halo vest immobilization in the elderly: a death sentence?. J Trauma 2005; 59 (02) 350-356 ; discussion 356–358
  • 20 Bredow J, Oppermann J, Kraus B. , et al. The accuracy of 3D fluoroscopy-navigated screw insertion in the upper and subaxial cervical spine. Eur Spine J 2015; 24 (12) 2967-2976
  • 21 Luther N, Iorgulescu JB, Geannette C. , et al. Comparison of navigated versus non-navigated pedicle screw placement in 260 patients and 1434 screws: screw accuracy, screw size, and the complexity of surgery. J Spinal Disord Tech 2015; 28 (05) E298-E303