Thromb Haemost 1974; 32(02/03): 432-440
DOI: 10.1055/s-0038-1647711
Original Article
Schattauer GmbH

A Method for Blood Platelet Homogenization Using the Aminco-French Pressure Cell

Autoren

  • Paul C. French

    1   Institute for Thrombosis Research, Rikshospitalet, and Electron Microscopic Laboratory, Rikshospitalet, Oslo 1, Norway
  • Randi Holme

    1   Institute for Thrombosis Research, Rikshospitalet, and Electron Microscopic Laboratory, Rikshospitalet, Oslo 1, Norway
Weitere Informationen

Publikationsverlauf

Received 12. Februar 1974

Accepted after resubmission 20. Juni 1974

Publikationsdatum:
24. Juli 2018 (online)

Summary

A rapid effective method for platelet homogenization using a pressure cell is described. With this method, almost complete homogenization of human platelets occurred without excessive solubilization of enzymes as compared to a pestle homogenization procedure where there was incomplete homogenization. Electron microscopy of pressure homogenates and fractions revealed well preserved organelles.