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Thromb Haemost 1976; 36(03): 532-536
DOI: 10.1055/s-0038-1648073
Original Article
Schattauer GmbH

The Influence of Ethanol Feeding on the Activities of Factors II, VII, VIII, IX and X in Rats

Jørg Mørland
1   Institute of Medical Biology, University of Tromsø, 9000 Tromsø, Norway
,
Turid Holm
1   Institute of Medical Biology, University of Tromsø, 9000 Tromsø, Norway
,
Hans Prydz
1   Institute of Medical Biology, University of Tromsø, 9000 Tromsø, Norway
› Author Affiliations
Further Information

Publication History

Received 07 July 1976

Accepted 22 July 1976

Publication Date:
03 July 2018 (online)

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Summary

The effect of chronic administration of ethanol to rats in a controlled regimen upon the activities of the coagulation factors II, VII, VIII, IX and X has been studied.

No significant differences were found for factor II, IX and X between the ethanol-treated rats and the control group given an isocaloric diet with carbohydrate replacing ethanol. Factor VII activity was somewhat higher and factor VIII activity decreased significantly in the experimental group when ethanol treatment was combined with an approximately two-fold increase in dietary polyunsaturated fatty acid.

 

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