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Thromb Haemost 1968; 19(03/04): 364-367
DOI: 10.1055/s-0038-1651214
Originalarbeiten – Original Articles – Travaux Originaux
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Kinetic Aspects of the Interaction of Blood Clotting Enzymes

IV. Kinetics of Competitive Inhibition in Clotting Tests
H. C Hemker
1   Laboratory of Coagulation Biochemistry, Hematology Section, Department of Internal Medicine, University Hospital, Leyden, The Netherlands
,
P. W Hemker
1   Laboratory of Coagulation Biochemistry, Hematology Section, Department of Internal Medicine, University Hospital, Leyden, The Netherlands
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Publication Date:
27 June 2018 (online)

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Summary

The enzyme kinetics of competitive inhibition under conditions prevailing in clotting tests are developed and a method is given to measure relative amounts of a competitive inhibitor by means of the t — D plot.

 

  • References

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