Calculation of Predictive Odds for Possible Carriers of Haemophilia

C. R. M Prentice; C. D Forbes; Sandra Morrice; A. D McLaren

doi:10.1055/s-0038-1651467

Thrombosis and Haemostasis, Inhaltsverzeichnis

Thromb Haemost 1975; 34(03): 740-747
DOI: 10.1055/s-0038-1651467

Original Article

Schattauer GmbH

Calculation of Predictive Odds for Possible Carriers of Haemophilia

Authors

C. R. M Prentice

¹Departments of Medicine and Statistics, Glasgow University, Scotland
C. D Forbes

¹Departments of Medicine and Statistics, Glasgow University, Scotland
Sandra Morrice

¹Departments of Medicine and Statistics, Glasgow University, Scotland
A. D McLaren

¹Departments of Medicine and Statistics, Glasgow University, Scotland

Abstract

Summary

Betting odds for possible carriers of haemophilia have been calculated using data derived from normal and known carrier populations. For each possible carrier the concentration of factor VIII-related antigen and factor VIII biological activity was measured and used to determine the probability of the individual being a carrier. The calculations indicated that, of the 32 possible carriers, 11 were likely to be normal (odds of more than 5:1) while 11 were likely to be haemophilia carriers (again odds of more than 5:1).

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Referenzen

References
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