Thromb Haemost 1975; 34(03): 763-769
DOI: 10.1055/s-0038-1651469
Original Article
Schattauer GmbH

Potato Inhibitors of Intrinsic Prothrombin Activators

K Worowski
1   Department of Biochemistry, Institute of Physiology and Biochemistry, Medical School, 15-952 Białystok, Poland
› Author Affiliations
Further Information

Publication History

Received 28 May 1975

Accepted 04 June 1975

Publication Date:
24 July 2018 (online)

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Summary

The potato protease inhibitors inhibit intrinsic prothrombin activators and trypsin activation of prothrombin. The inhibitors 5a and 5b are responsible for the intrinsic prothrombin activator inhibition. This inhibition is progressive. No inhibition by these inhibitors of tissue thromboplastin activation of prothrombin or thrombin activity was observed.